ArticleFrontiers in immunology2025
Preoperative malnutrition predicts poor early immune recovery following gynecologic cancer surgery: a retrospective cohort study and risk nomogram development.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Predictors of Mortality in Pediatric Cardiac Intensive Care Units: A Systematic Review and Exploratory Meta-Analysis.Cureus · 2026Review
- Physical examination-indicated repeat cerclage in singleton pregnancies: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Development and internal validation of a clinical nomogram for predicting bronchopulmonary dysplasia in preterm infants.Experimental and therapeutic medicine · 2026Article
- Multimodal analgesia strategies enhance postoperative recovery and mitigate inflammatory responses in women undergoing elective surgery for endometrial cancer: a retrospective cohort study.Frontiers in oncology · 2026Article
- The value of perioperative nutritional risk stratification in the prevention of surgical site infection: precision application from GLIM/PG-SGA to PNI, CONUT, and GNRI.Frontiers in nutrition · 2026Review
- Article
- The microbial conductor of cancer hallmarks: intratumoral microbiome as a multidimensional oncogenic modulator.Frontiers in microbiology · 2025Review
- Neutrophil-to-lymphocyte ratio in females as a predictor of embryo acquisition outcomes after IVF/ICSI treatment: a retrospective study.Frontiers in endocrinology · 2025Article
- Maternal inflammatory biomarkers and neonatal characteristics as predictors of bronchopulmonary dysplasia in preterm infants: a retrospective cohort study.Frontiers in medicine · 2025Article
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6 authors.
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Abstract
Background: Malnutrition is prevalent in patients undergoing gynecologic cancer surgery and may compromise postoperative immune competence. However, its specific association with early immune recovery remains unclear, and validated predictive tools are lacking. Methods: This retrospective cohort study included 1,245 women who underwent curative surgery for cervical, endometrial, or ovarian cancer between March 2021 and September 2023. Preoperative nutritional status was assessed using the Patient-Generated Subjective Global Assessment (PG-SGA), and patients were stratified into well-nourished and malnourished groups. Poor immune recovery was defined as lymphocyte count <1.0 ×10 Results: Malnourished patients had a significantly higher risk of poor immune recovery (36.6% Conclusion: Malnutrition is an independent risk factor for impaired early immune recovery after gynecologic cancer surgery. Our predictive model offers a clinically applicable tool to identify high-risk patients and support personalized perioperative management. Future prospective validation is warranted.
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