ArticleJTCVS open2025
Hemodynamic considerations of ipsilateral versus contralateral cannulation with venoarterial extracorporeal membrane oxygenation.
Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Modifying a traditional femoral venoarterial extracorporeal membrane oxygenation cannulation strategy and circuit to improve distal limb hemodynamics.JTCVS open · 2026Article
- Retrograde perfusion of the dorsalis pedis artery versus traditional distal perfusion catheter use in venoarterial extracorporeal membrane oxygenation.JTCVS open · 2026Article
- Flow benefits of pediatric arterial cannulae versus introducer sheaths as distal perfusion catheters in venoarterial extracorporeal membrane oxygenation.JTCVS open · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Patients on venoarterial extracorporeal membrane oxygenation undergoing ipsilateral cannulation may develop distal limb ischemia. We postulate 2 clinical questions: (1) Would contralateral cannulation have a lower distal limb ischemia rate than ipsilateral? (2) Do larger diameter arterial and venous cannulae increase the risk of distal limb ischemia independent of cannulation approach? A dynamic mock loop study investigating the potential hemodynamic benefits and risks of ipsilateral versus contralateral cannulation and cannulae size is presented. Methods: The hemodynamics of ipsilateral versus contralateral cannulation with arterial (15F, 17F) and venous (23F, 25F) cannulae combinations over pump speeds (0-3000 rpm) delivering 0 to 3.5 L/min extracorporeal membrane oxygenation flow was evaluated in an adult heart failure dynamic mock loop. Results: In the dynamic mock loop, contralateral cannulation was more effective than ipsilateral at increasing flow and decreasing pressure in both limbs. Increasing arterial cannula size from 15F to 17F enabled higher extracorporeal membrane oxygenation flows but at the expense of greater intravascular obstruction. Venous cannula size (23F, 25F) had no effect on limb hemodynamics. Conclusions: Our dynamic mock loop findings are consistent with reported Extracorporeal Life Support Organization Registry data and others, while also suggesting added hemodynamic benefits of venoarterial extracorporeal membrane oxygenation using a contralateral approach with the potential for better clinical outcomes.
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