ReviewDiscover mental health2025
Psychiatric comorbidities in HIV/AIDS patients and its overlap with neurological disorders.
Review in Discover mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- The efficacy and mechanism of an integrated mindfulness-based programme on posttraumatic stress disorder among people with HIV: a randomized controlled trial with 3-month follow up.European journal of psychotraumatology · 2026Trial
- Clinical and behavioral predictors of HIV-associated neurocognitive disorder among people with HIV who use substances: a secondary analysis of the HOPE trial.Journal of neurovirology · 2026Trial
- Artificial intelligence-based diagnostic model for schizophrenia in individuals living with HIV.Frontiers in psychiatry · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of psychiatric and neurological disorders in populations with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) presents significant public health concerns including impaired quality of life, reduced antiretroviral therapy (ART) adherence, and elevated morbidity and mortality rates. Research suggests that these correlations translate to millions of people globally, given that over 25 million people are living with HIV/AIDS in the African region alone.
objectiveThis article explores the overlap in clinical presentation and pathophysiology between psychiatric and neurological conditions and seeks to fill current knowledge gaps regarding their co-occurrence, misdiagnosis, and impact on treatment outcomes.
methodsA comprehensive literature review was conducted employing electronic search databases comprising PubMed/MEDLINE, ResearchGate, and related databases, using keywords such as “psychiatric disorders,” “neurological disorders,” “HIV,” “AIDS,” and “comorbidities”. Studies were selected based on relevance to the overlap of psychiatric and neurological conditions in HIV/AIDS.
resultsNeurological disorders like HIV-Associated Neurocognitive Disorders (HAND) were observed in 20–50% of HIV/AIDS patients. Similarly, the prevalence of psychiatric symptoms, such as depression and anxiety, among HIV/AIDS patients was reported at 32.9% and 27.4% respectively. Also, overlapping pathophysiological processes, such as neuroinflammation, immune dysregulation, and HIV-related neurotoxicity, were identified as common mechanisms underpinning both psychiatric and neurological disorders in HIV/AIDS patients.
conclusionMultidisciplinary collaborations are warranted to create tailored antiretroviral therapy regimens that minimize neurotoxicity and further investigate the neuropsychiatric overlap to enhance diagnostic accuracy and patient outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.