Evidence map›Paper›PMID 41168558›Full record

ArticleAnnals of intensive care2025

Multimodal assessment of peripheral perfusion in critically ill patients: a pilot study.

Zoé Demailly, Elena Modica, Eva Vitali, Francisco Sousa, Carlotta Dragoni, Irene Sbaraini Zernini, Claudio Annicchiarico, Charles Dehout, Fabienne Tamion, Emmanuel Besnier and 3 more

Abstract read
In one paragraph

Article in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zoé DemaillyDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium. zoe.demailly@chu-rouen.fr.ORCID http://orcid.org/0000-0001-9768-0193
Elena ModicaDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Eva VitaliDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Francisco SousaDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Carlotta DragoniDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Irene Sbaraini ZerniniDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Claudio AnnicchiaricoDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Charles DehoutDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Fabienne TamionMedical Intensive Care Unit, CHU Rouen, Normandie Université, Rouen, 76000, France.
Emmanuel BesnierMedical Intensive Care Unit, CHU Rouen, Normandie Université, Rouen, 76000, France.
Hassane NjimiDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Elaine Cavalcante Dos SantosDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Fabio Silvio TacconeDepartment of Intensive Care, Erasme Hospital, Brussels University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImpaired peripheral perfusion is linked to poor outcomes in critically ill patients, but the relationships among common bedside assessment tools remain unclear. This study aimed to evaluate whether these parameters provide overlapping or complementary prognostic information across ICU subgroups.

methodsAdult ICU patients with an expected stay ≥ 3 days were included. On day 1, six peripheral perfusion parameters were simultaneously measured: Peripheral Perfusion Index (PPI), Mottling Score (MS), Capillary Refill Time (CRT), central-to-peripheral temperature gradient (ΔT), Skin Blood Flow at basal temperature (SBF

resultsFifty-five patients were included (median age 64; 65.5% male). Circulatory shock (36.4%) was the leading admission cause, followed by acute brain injury (ABI; 29.1%) and acute respiratory failure (ARF; 25.4%). Strong correlations were found between PPI, CRT, SBF

conclusionsMost bedside peripheral perfusion parameters were strongly interrelated, particularly PPI, SBF

Indexed as

Critically illHaemodynamicIntensive care unitMicrocirculatory perfusionPeripheral perfusion

Identifiers

PMID41168558
PMCPMC12575891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.