Observational studyEuropean radiology2026
Demographic and cardiovascular risk factors associated with blood flow characteristics of the left atrium and left atrial appendage.
Observational study in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- 4D Flow MRI Characterization of Left Atrial Vortical Flow in Atrial Fibrillation Following Catheter Ablation.Journal of imaging · 2026Article
- Left atrial strain on 2D-STE in pediatric dilated cardiomyopathy.Echo research and practice · 2026Article
- Determinants of Impaired Left Atrial Hemodynamics in Paroxysmal Atrial Fibrillation: A 4D Flow MRI Study.Journal of imaging · 2026Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
objectivesImpaired left atrium (LA) and left atrial appendage (LAA) hemodynamics are risk factors (RF) for atrial thrombus formation and stroke. They can be assessed in vivo using 4D-flow-MRI; however, most studies involve clinical patient samples. We aimed to investigate demographic and cardiovascular (CV)-RF associations with LA and LAA hemodynamics in an observational study sample. MATERIAL AND
methodsParticipants from the multi-ethnic study of atherosclerosis from our institution were approached to undergo cardiac MRI, including 4D-flow-MRI. LA and LAA volume, blood stasis (%voxel with velocity < 0.1 m/s), and peak velocity (PV, top 5% of voxels) were calculated. CV-RF (demographics, history of atrial fibrillation (AF), body mass index (BMI), etc.) were available through study records and investigated in multivariable linear regression models.
resultsOne hundred fifty-eight participants were included (age: 72.8 ± 7.3 years, 53% female). Higher age and AF were associated with lower PV
conclusionWe identified RF associated with impaired LA and LAA hemodynamics in an observational study cohort. KEY POINTS: Question Are there associations of demographic and CV factors with impaired atrial hemodynamics from 4D-flow cardiac MRI? Findings 4D-flow MRI identified, amongst others, higher age, race, history of AF, and BMI in a sub-cohort of the Multi-Ethnic Study of Atherosclerosis. Clinical relevance Understanding risk factor associations with atrial hemodynamics could aid in identifying subclinical atrial thrombus formation risks, potentially allowing for earlier preventive strategies against diseases such as stroke in diverse populations.
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