Evidence map›Paper›PMID 41168441›Full record

ArticleCommunications medicine2025

Exploring predictors of post-COVID-19 condition among 810 851 individuals in Sweden.

Yiyi Xu, Huiqi Li, Robert Sigström, Lisa Lundberg-Morris, Magnus Gisslén, Simon B Larsson, Fredrik Nyberg, Maria Bygdell

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiyi XuSchool of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Huiqi LiSchool of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0002-1127-0829
Robert SigströmDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lisa Lundberg-MorrisDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0002-5920-3801
Magnus GisslénDepartment of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Simon B LarssonDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0002-0964-6137
Fredrik NybergSchool of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0003-0892-5668
Maria BygdellSchool of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. maria.bygdell@gu.se.ORCID http://orcid.org/0000-0002-0737-8642

Funding

Forskningsrådet om Hälsa, Arbetsliv och Välfärd (Swedish Research Council for Health, Working Life and Welfare) 2022-00444Svenska Sällskapet för Medicinsk Forskning (Swedish Society for Medical Research) PD20-0012Vetenskapsrådet (Swedish Research Council) 2022-06395
6 · The paper itself

Abstract

backgroundLong-term effects of COVID-19 can place burden on individuals, healthcare, and society. We aimed to evaluate the importance of a wide range of potential risk factors for being diagnosed with post-COVID-19 condition (PCC).

methodsWe used data from national and regional registers and databases for all adult residents in the two largest regions in Sweden. Individuals with a first COVID-19 between 1 August 2020 and 9 February 2022 were included and followed until PCC diagnosis, censoring (death or migration), or 30 November 2023. Using Cox proportional hazards models and backwards stepwise selection, we evaluated a large set of risk factors including sociodemographic data, comorbidities, healthcare contact behaviors, COVID-19-related factors, as well as PCC in family and cohabitants (as proxies for genetics and shared environment).

resultsWe include 810,851 individuals (age range 18-106 years and 53.3% women), of whom 1.4% are diagnosed with PCC during follow-up. Female sex, older age, being born outside Sweden, higher educational attainment, essential workers, having comorbidities such as thromboembolic disease, asthma, fibromyalgia, depression/anxiety, and stress-related disorders, being infected earlier in the study period, experiencing severe acute COVID-19, not being vaccinated before COVID-19, and having a relative or a cohabitant with PCC are associated with an increased risk of being diagnosed with PCC.

conclusionsIn this large population-based cohort study, our exploratory analysis reveals several risk factors for being diagnosed with PCC. Our findings can serve as a basis for future targeting of preventive measures against PCC.

Identifiers

PMID41168441
PMCPMC12575654

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.