Evidence map›Paper›PMID 41168434›Full record

ArticleMikrochimica acta2025

Highly sensitive electrochemical aptasensor for ochratoxin A detection in barley flour: a novel nanocomposite approach with RGO-Cu-Ni-BTC-MOF and hematoxylin.

Elaheh Amini-Nogorani, Hamid R Zare, Fahime Jahangiri-Dehaghani, Ali Benvidi

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Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Elaheh Amini-NogoraniDepartment of Chemistry, Yazd University, Yazd, 89195-741, Iran.
Hamid R ZareDepartment of Chemistry, Yazd University, Yazd, 89195-741, Iran. hrzare@yazd.ac.ir.
Fahime Jahangiri-DehaghaniDepartment of Chemistry, Yazd University, Yazd, 89195-741, Iran.
Ali BenvidiDepartment of Chemistry, Yazd University, Yazd, 89195-741, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An electrochemical aptasensor is presented. It is designed for the detection of ochratoxin A (OTA), employing a nanocomposite of reduced graphene oxide (RGO) and a bimetallic copper-nickel 1,3,5-benzene tricarboxylate metal-organic framework (Cu-Ni-BTC-MOF) to achieve enhanced signal amplification. Additionally, hematoxylin was used as an electroactive label to facilitate the generation of the electrochemical signal. The OTA-specific aptamer was immobilized onto the RGO-Cu-Ni-BTC-MOF and subsequently hybridized with its complementary DNA (cDNA). Hematoxylin was intercalated within the resulting aptamer-cDNA duplex. The analytical signal was determined as the difference in the electrochemical responses of accumulated hematoxylin before and after incubation with OTA. Differential pulse voltammetry (DPV) was employed for quantitative determination, revealing a linear detection range of 1.0 fg mL

Indexed as

Aptamers, NucleotideBiosensing TechniquesElectrochemical TechniquesFlourHordeumMetal-Organic FrameworksNanocompositesOchratoxinsCopperFood ContaminationGraphiteLimit of DetectionNickelAptamers, NucleotideCoppergraphene oxideGraphiteMetal-Organic FrameworksNickelochratoxin AOchratoxinsBarley flourBimetallic metal–organic frameworkDifferential pulse voltammetryElectrochemical aptasensorModified glassy carbon electrodeOchratoxin A (OTA)Reduced graphene oxide (RGO)

Identifiers

PMID41168434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.