ArticleCommunications medicine2025
A prospective cohort analysis from Germany shows transition into adulthood is an underestimated vulnerable period for children with overweight/obesity.
Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- European Society for Paediatric Endocrinology and European Society of Endocrinology Joint Clinical Practice Guidance for Healthcare Transition from Paediatric to Adult Endocrine Care.Hormone research in paediatrics · 2026Guideline
- National Trends and Outcomes of Metabolic and Bariatric Surgery in Adolescents: Insights from the Israeli National Bariatric Surgery Registry.Obesity surgery · 2026Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundEven though the transition from adolescence to adulthood is a vulnerable and crucial period for young individuals with chronic conditions, it remains poorly studied in obesity. We comprehensively characterized the transition of children with overweight/obesity from childhood to adult care.
methodsData from an adulthood follow-up of the Leipzig childhood obesity cohort (N = 209, mean age at follow-up 24.9 years) were analyzed and related to the respective childhood data. Assessments comprised anthropometrics, oral glucose tolerance testing, carotid ultrasonography, 24 h blood pressure monitoring, liver elastography and questionnaires on psychosocial background, quality of life and transition process.
resultsHere we show that childhood onset overweight/obesity persists in 93.3% until adulthood. However, most patients (55.6%) who move into a higher BMI category during transition still report that things are going better with their weight during adulthood. Complications are frequent among young adults (overall 83.7%, (pre)diabetes 11.4%, hypertension 24.5%, elevated intima-media thickness 82.2%, fatty liver disease 10.2%, regular intake of medication 45%) and deteriorate with progressing weight gain from childhood to adulthood. 87% of adults have not been aware of one or more of these complications before. Most participants report physical complaints (57.3%) and symptoms of depression/anxiety (52.0%). The majority (94.3%) lose contact with specialized obesity care during transition with lack of knowledge being the most frequent reason. Instead, general practitioners are regularly consulted by 50.7%, but obesity is seldom addressed as a topic (22.6%). Better management of the transition process is desired by 26.7% of participants.
conclusionsChildren with overweight/obesity carry a substantial health burden into adulthood which is often not perceived. Structured transition approaches are needed to address obesity as a chronic condition.
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