Evidence map›Paper›PMID 41168229›Full record

ArticleScientific reports2025

Microwave therapy promotes wound healing in diabetic mice by activating IL-33/ST2-mediated M2 macrophage polarization.

Miaoxin He, Xinglan Huang, Tao Liu, Qian Yang, Yanfang Zheng, Yunxue Wu, Yanni Zhang, Yimin Liang, Zhongmin Liao, Shufen Peng and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Miaoxin HeGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 528405, China.
Xinglan HuangDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Tao LiuGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 528405, China.
Qian YangDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Yanfang ZhengDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Yunxue WuDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Yanni ZhangDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Yimin LiangDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Zhongmin LiaoDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Shufen PengDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China.
Hui YinGuangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou, 528405, China. huiyin0103@163.com.
Rongguo HeDepartment of Dermatology, Guangzhou Twelfth People's Hospital, 1 Tianqiang Road, Tianhe District, Guangzhou, 510620, Guangdong, China. 459363210@qq.com.

Funding

Guangzhou Science and Technology Bureau project NO.2023A03J0972
6 · The paper itself

Abstract

Chronic non-healing wounds are among the most common complications of diabetes, highlighting the urgent need for effective and accessible therapeutic strategies. Although microwave therapy has shown promise in promoting tissue repair, its underlying mechanisms in diabetic wound healing remain unclear. This study investigated the therapeutic effects of microwave therapy on diabetic wound healing and its potential modulation of the Interleukin-33 (IL-33) /ST2 signaling pathway. Full-thickness excisional wounds were established in C57BL/6 mice, categorized into normal control / wild-type (CON/WT), diabetic (DM), and ST2-deficient (ST2

Indexed as

Diabetes Mellitus, ExperimentalInterleukin-1 Receptor-Like 1 ProteinInterleukin-33MacrophagesMicrowavesWound HealingAnimalsCell MovementHumansKeratinocytesMacrophage ActivationMaleMiceMice, Inbred C57BLMice, KnockoutRAW 264.7 CellsIl1rl1 protein, mouseIl33 protein, mouseInterleukin-1 Receptor-Like 1 ProteinInterleukin-33Diabetic wound healingIL-33/ST2 signalingImmunomodulationM2 macrophagesMicrowave therapy

Identifiers

PMID41168229
PMCPMC12575834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.