Evidence map›Paper›PMID 41168204›Full record

ArticleScientific reports2025

Exploring the availability and acceptability of hormone replacement therapy in LMICs using insights of pharmacists (MARIE Sri Lanka WP2a).

Vindya Pathiraja, Om Kurmi, Teck-Hock Toh, George Uchenna Eleje, Fred Tweneboah-Koduah, Bernard Mbwele, Paula Briggs, Kathleen Riach, Sharron Hinchliff, Kristina Potocnik and 16 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  2. Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Vindya PathirajaUniversity of Ruhuna, Matara, Sri Lanka.
Om Kurmi *Coventry University, Coventry, UK.
Teck-Hock Toh *Sibu Hospital, Sarawak, Malaysia.
George Uchenna Eleje *Nnamdi Azikiwe University, Awka, Nigeria.
Fred Tweneboah-Koduah *Narh-Bita Hospital, Tema, Ghana.
Bernard Mbwele *University of Dar es Salaam -Mbeya College of Health and Allied Sciences (UDSM-MCHAS), DMbeya, Tanzania.
Paula BriggsLiverpool Women's Hospital Foundation NHS Trust, Liverpool, UK.
Kathleen RiachUniversity of Glasgow, Glasgow, UK.
Sharron HinchliffUniversity of Sheffield, Sheffield, UK.
Kristina PotocnikUniversity of Edinburgh, Edinburgh, Scotland, UK.
Vikram TalaulikarUniversity College London Hospitals NHS Foundation Trust, London, UK.
Lucky SaraswatUniversity of Aberdeen, Aberdeen, Scotland, UK.
Jian Qing ShiSouthern University of Science and Technology, Shenzhen, China.
Sohier ElneilUniversity College London Hospitals NHS Foundation Trust, London, UK.
Nihal Al-RiyamiSultan Qaboos University, Al-khod, Oman.
Yassine BoucharebSultan Qaboos University, Al-khod, Oman.
Ashish ShettyUniversity College London Hospitals NHS Foundation Trust, London, UK.
Cristina Benetti-PintoUniversity of Campinas, UNICAMP, Campinas, Brazil.
Helen Felicity KempTrauma Healing Together, Perth, Scotland, UK.
Jude SiongSibu Hospital, Sarawak, Malaysia.
David Chibuike IkwukaUniversity of Rwanda, Kigali, Rwanda.
Tharanga MudaligeUniversity of Ruhuna, Matara, Sri Lanka.
Lanka DasanayakeUniversity of Ruhuna, Matara, Sri Lanka.
Peter PhiriHampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK.
Nirmala RathnayakeUniversity of Ruhuna, Matara, Sri Lanka. nirmalarathnayake@ahs.ruh.ac.lk.
Gayathri DelanerolleUniversity of Birmingham, Birmingham, UK. g.delanerolle@bham.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hormone Replacement Therapy (HRT) remains underutilised and under-researched in low- and middle-income countries (LMICs), despite its potential to alleviate menopausal symptoms. This study explored pharmacists' perspectives on the use, cost, and availability of HRT across six LMICs. A cross-sectional survey was conducted from January 1 to March 31, 2025, as part of the Global Menopause Project. Pharmacists working in community, hospital, and private sector settings in Malaysia, Sri Lanka, Nepal, Nigeria, Ghana, and Tanzania were recruited. Participants completed an anonymous online questionnaire. The questionnaire was piloted prior to dissemination, assessed HRT availability, pricing, and perceived barriers to use. A total of 331 pharmacists responded: Ghana (18·4%), Sri Lanka (17·5%), Tanzania (16·9%), Nepal (16·6%), Malaysia (15·4%), and Nigeria (15·1%). The respondents were almost equally distributed between sexes (50·8% were female), and most were aged 26-35 years (49·0%). The majority worked in private community pharmacies (41·7%) or government hospitals (32·6%), and 57·4% were based in urban areas. From the sample, 68·9% of pharmacists reported that HRTs were available for dispensing in their respective countries (highest proportion was reported in Nepal, 92·7% and lowest in Nigeria, 42%). HRT costs varied widely, with Sri Lanka reporting the highest prices and Malaysia the lowest. Key barriers identified included low health literacy, economic constraints, and limited healthcare access. Significant disparities exist in HRT access, availability and affordability across LMICs, with urban-rural gaps further compounding inequities. Pharmacists' insights underscore the urgent need for inclusive, equitable strategies in menopausal care and women's health policy in resource-limited settings.

Indexed as

Hormone Replacement TherapyPharmacistsAdultCross-Sectional StudiesDeveloping CountriesFemaleHealth Services AccessibilityHumansMalaysiaMaleMenopauseMiddle AgedNepalSri LankaSurveys and QuestionnairesTanzaniaAcceptabilityAvailabilityHormone replacement therapyLow- and Middle-Income countriesPharmacists

Identifiers

PMID41168204
PMCPMC12575872

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.