ReviewNPJ microgravity2025
Review of microgravity's impact on cardiovascular and nervous systems in space exploration.
Review in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Impact of Microgravity on Cytoskeletal Dynamics, Protein Transport, and Signaling Networks: Potential Therapeutic Opportunities for Skin Health.International journal of molecular sciences · 2026Review
- Artificial Intelligence for In-Flight Detection of Space-Related Ocular Trauma: Bridging Diagnostic Gaps in Microgravity.Vision (Basel, Switzerland) · 2026Review
- Article
- Cardiovascular Exercise Physiology Under Hypoxia, Microgravity, and Heat Stress: A Review with Public Health Implications.International journal of environmental research and public health · 2026Review
- Microgravity- induced organ and system-level deconditioning: a network physiology perspective.Frontiers in network physiology · 2026Review
- Monitoring and modulating interconnected physiological systems in space using portable closed-loop technologies.Frontiers in network physiology · 2026Article
- The hierarchical stratum response system of organism to microgravity during spaceflight.Military Medical Research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microgravity induces cardiovascular adaptations, including fluid shifts, cardiac remodeling, and autonomic changes. Acute responses involve increased preload and stroke volume, while chronic adaptations include cardiac atrophy, vascular remodeling, and autonomic impairment, contributing to post-flight orthostatic intolerance. These changes raise concerns for long-term astronaut health. Understanding these adaptations is crucial for developing countermeasures to mitigate spaceflight-related cardiovascular risks and may offer insights applicable to terrestrial medicine.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.