SynthesisInternational journal of dermatology2026
Global Patterns of Comorbidities Among Patients With Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis.
Synthesis in International journal of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global Patterns of Comorbidities Among Patients With Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis.International journal of dermatology · 2026Pooled it
- Illness Acceptance in Patients with Hidradenitis Suppurativa Depends on Disease Severity and Psychosocial Parameters: An Observational Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Hidradenitis Suppurativa Changes Major Life Decisions of Affected Patients: A Cross-sectional Study.Acta dermato-venereologica · 2026Article
- A Cross-Sectional Study on Relationships Between Depression and Anxiety in Hidradenitis Suppurativa Patients and Disease Severity, Subjective Symptoms and Quality of Life.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin disorder increasingly recognized as a systemic disease with diverse comorbidities. While several comorbid conditions are well documented, regional differences in prevalence remain unclear.
objectiveThe aim of this study was to evaluate regional variation in major comorbidities among HS patients, including diabetes, hypertension, depression, smoking, thyroid disorders, acne, obesity, psoriasis, and inflammatory bowel disease.
methodsWe performed a meta-analysis of proportions using a generalized linear mixed model with a binomial distribution and logit link to compare the prevalence of HS-associated comorbidities across North America, Europe, and the Middle East/Asia. Analyses were stratified by adult and pediatric populations, with regional N-values incorporated.
resultsSignificant regional differences were observed in metabolic, endocrine, and psychiatric comorbidities. North American patients had higher odds of diabetes compared to Europe (odds ratio [OR] 1.92) and hypertension compared to the Middle East/Asia (OR 2.99). Depression and thyroid disorders were more common in North America (OR 3.46 and 2.32) and Europe (OR 3.19 and 4.01) compared to the Middle East/Asia. Smoking was more prevalent in Europe compared to North America (OR 0.28) and the Middle East/Asia (OR 2.26). Among pediatric patients, anxiety (OR 0.05) and depression (OR 0.16) were more common in North America, while smoking was more frequent outside North America (OR 12.67).
conclusionsRegional variation in comorbidity prevalence likely reflects differences in lifestyle, diet, sociocultural norms, healthcare literacy, and access to care. Recognizing these patterns may support earlier identification, guide preventive efforts, and inform individualized management strategies in HS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.