Evidence map›Paper›PMID 41167703›Full record

SynthesisIn vivo (Athens, Greece)

Beyond Surgical Injury: Systemic Etiologies of Recurrent Laryngeal Nerve Palsy.

Efstratios Kofopoulos-Lymperis, Kalliopi Stavrati, Dimitrios Papaconstantinou, Emmanouil Pikoulis, Melpomeni Peppa, Konstantinos Chaidas, Alexander Delides, Konstantinos Nastos

Abstract readSystematic Review
In one paragraph

Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Efstratios Kofopoulos-LymperisThird Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Kalliopi StavratiEvgenideio Hospital, Athens, Greece.
Dimitrios PapaconstantinouThird Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece; dimpapakos@webmail.uoa.gr.
Emmanouil PikoulisThird Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Melpomeni PeppaEndocrine Unit, Second Propaedeutic Department of Internal Medicine and Research Institute, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos ChaidasENT Department, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece.
Alexander Delides2 Otolaryngology Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos NastosThird Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recurrent laryngeal nerve (RLN), a branch of the vagus nerve, plays a crucial role in phonation, respiration, and airway protection. Dysfunction of the RLN can result from various factors, including trauma, surgery, endotracheal intubation, infection, and systemic diseases, leading to clinical symptoms such as hoarseness, stridor, dysphagia, and severe respiratory distress. This systematic review examines the impact of systemic diseases on RLN function. Through an analysis of cases from the English literature, the review demonstrates that RLN dysfunction in the context of systemic diseases is multifactorial, often involving complex pathophysiology. Key findings highlight that RLN dysfunction can be caused by autoimmune, inflammatory, and neurological conditions, as well as medications. The review discusses the diagnostic challenges associated with these conditions, as symptoms often overlap with other disorders, complicating accurate diagnosis. The importance of early recognition and a multidisciplinary approach to management is emphasized, with the goal of improving patient outcomes. Ultimately, increased awareness and understanding of the diverse causes of RLN dysfunction in systemic diseases are essential for effective diagnosis and management.

Indexed as

Recurrent Laryngeal Nerve InjuriesVocal Cord ParalysisHumansRecurrent Laryngeal Nerveautoimmune neuropathyRecurrent laryngeal nervereviewsystemic diseasevocal cord paralysis

Identifiers

PMID41167703
PMCPMC12588220

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.