ArticleIn vivo (Athens, Greece)
Epidemiological Profile of Hepatocellular Carcinoma in Brazil.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The global epidemiology of hepatocellular carcinoma.Hepatology communications · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimHepatocellular carcinoma (HCC) is a significant global health concern, ranking as the sixth most common neoplasm and the third leading cause of cancer-related deaths. This study aimed to consolidate data on HCC to provide a comprehensive epidemiological profile in Brazil. PATIENTS AND
methodsThis retrospective study analyzed secondary data extracted from the Mortality Information System (SIM), Hospital Cancer Registry (RHC), and Population-Based Cancer Registry (RCBP) from 2000 to 2019. The analysis included 26,349 HCC cases, incorporating variables such as age, sex, stage at diagnosis, treatment modalities, and mortality rates. Statistical analyses were performed using the chi-square test, Student's
resultsThe number of HCC cases in Brazil has progressively increased over time. Most patients were male (16,631 of 26,349; 63.1%), with a mean age of 60-61 years. A large proportion of patients were diagnosed at an advanced stage (4,991 of 10,645; 46.9%), which limited curative treatment options. Only 38.7% (10,064) of 26,349 patients received any form of treatment. Mortality was significantly increased, 60.6% (5,891 of 9,727 cases).
conclusionThese findings highlight the critical need for improved epidemiological surveillance, expanded screening programs, and standardized diagnostic and treatment protocols for HCC in Brazil. The high prevalence of late-stage diagnoses and limited access to treatment underscores the urgent need to implement effective public health policies to promote early detection and improve disease management.
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