Evidence map›Paper›PMID 41167687›Full record

SynthesisIn vivo (Athens, Greece)

Integrated Multimodal Approaches in Pediatric Palliative Oncology: A Systematic Review Focused on Infants and Toddlers.

Angela Prendin, Martina Costa, Gloria Angela Baracco, Vincenzo Andretta, Marco Cascella, Maria Rosaria Muzio, Sabrina Bimonte, Ferdinando Spagnuolo, Valentina Cerrone

Abstract readSystematic Review
In one paragraph

Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angela PrendinResearch grant, University Hospital of Padua, Padua, Italy.
Martina CostaIndependent researcher, University Hospital of Padua, Padua, Italy.
Gloria Angela BaraccoPsychologist, University Hospital of Padua, Padua, Italy.
Vincenzo AndrettaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Marco CascellaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Maria Rosaria MuzioDivision of Infantile Neuropsychiatry, UOMI-Maternal and Infant Health, ASL NA3 SUD Torre del Greco, Naples, Italy.
Sabrina BimonteDepartment of Anesthesia and Critical Care, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy; s.bimonte@istitutotumori.na.it.
Ferdinando SpagnuoloTerapia Intensiva Neonatale A.O.U. Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
Valentina CerroneOncology Unit, University-Hospital of Salerno, Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPediatric palliative care, particularly in oncology, is aimed at improving the quality of life for children with cancer and other life-limiting conditions. With an increase in the pediatric population eligible for such care, the need for multidisciplinary approaches and the integration of personalized care strategies emerges. MATERIALS AND

methodsWe conducted a systematic review to analyze the available evidence regarding the most effective interventions, with particular attention to pharmacological assistance, home management, and the central role of the nurse in childcare. The literature search was conducted through the databases PubMed, CINAHL, Google Scholar, and Scopus, encompassing studies published between 2000 and 2024, with a focus on children aged 0 to 2 years.

resultsTen key studies were identified that highlighted the importance of the multimodal approach in pediatric palliative care. The main interventions include the use of sedative drugs for symptom management, electronic symptom monitoring to improve family involvement, the importance of pain therapy, and the effectiveness of home care, as preferred by most families.

conclusionA care model that integrates multiple strategies, supported by a multidisciplinary team, is essential to ensure the optimal well-being of children in critical conditions. However, the paucity of specific studies on the 0-2 age group and the lack of standardized protocols represent significant limitations in clinical practice.

Indexed as

Medical OncologyNeoplasmsPalliative CareChild, PreschoolCombined Modality TherapyHumansInfantInfant, NewbornPain ManagementPediatricsQuality of LifeOncologypainpalliative carepediatricsreview

Identifiers

PMID41167687
PMCPMC12588247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.