Observational studyIn vivo (Athens, Greece)
Effectiveness of Scalp-cooling Therapy for Preventing Chemotherapy-induced Alopecia in Patients With Breast Cancer: A Prospective Observational Study Focusing on Scalp, Eyebrow, and Eyelash Hair Loss.
Observational study in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Objective quantification of chemotherapy-induced madarosis: a pilot study of an automated computer vision pipeline for eyebrow density assessment.Scientific reports · 2026Article
- Patient-reported Outcomes of Adverse Events After Perioperative Chemotherapy for Breast Cancer: A Prospective Observational Study.Cancer diagnosis & prognosisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimChemotherapy-induced alopecia (CIA) is a significant concern for patients with breast cancer (BC). Although scalp-cooling therapy has shown efficacy in reducing scalp hair loss, its effects on eyebrow and eyelash preservation have been unclear. PATIENTS AND
methodsWe conducted a prospective observational study of 154 patients with BC who received perioperative chemotherapy from 2016 to 2024. Seventeen of these patients underwent scalp cooling using the Paxman Scalp Cooling System (Paxman, Houston, TX, USA). Patient-reported outcomes were assessed via questionnaires evaluating the degree of hair loss at the scalp, eyebrows, eyelashes, and body hair.
resultsScalp cooling significantly reduced the incidence of severe hair loss (score 4-5) at the scalp (
conclusionScalp-cooling therapy is effective for preventing severe scalp hair loss and may offer partial protection against eyebrow and eyelash alopecia. These findings support its broader application in BC care to enhance patients' quality of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.