Evidence map›Paper›PMID 41167676›Full record

ArticleIn vivo (Athens, Greece)

Expression and Clinical Significance of Sideroflexin 4 (SFXN4) in Colorectal Cancer.

Levar Shamoun, Jan Dimberg, Kristin A F Geijerstam, Elin Moltubak, Kalle Landerholm, Dick Wågsäter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Levar ShamounDepartment of Laboratory Medicine and Pathology, Ryhov Hospital, Jönköping, Sweden; Levar.Shamoun@rjl.se.
Jan DimbergDepartment of Clinical Diagnostics, School of Health and Welfare, Jönköping University, Jönköping, Sweden.
Kristin A F GeijerstamDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Elin MoltubakDepartment of Surgery, Ryhov Hospital, Region Jönköping County, Jönköping, Sweden.
Kalle LanderholmDepartment of Surgery, Ryhov Hospital, Region Jönköping County, Jönköping, Sweden.
Dick WågsäterDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSideroflexin 4 ( PATIENTS AND

methodsSFXN4 protein and mRNA expression in cancer and paired normal tissues was determined in patients with CRC using enzyme-linked immunosorbent assay (ELISA) and RT-qPCR. Immunohistochemical staining was used to study the cell type origin of the SFXN4 expression.

resultsThe protein and mRNA level of

conclusionThe findings indicate the importance of SFXN4 in colorectal carcinogenesis and extended studies are necessary to elucidate its role as a prognostic biomarker.

Indexed as

Biomarkers, TumorColorectal NeoplasmsGene Expression Regulation, NeoplasticAgedClinical RelevanceFemaleHT29 CellsHumansImmunohistochemistryMaleMiddle AgedPrognosisRNA, MessengerBiomarkers, TumorRNA, MessengerCarcinogenesisclinical parameterscolorectal cancermitochondriaproliferationzmynd15

Identifiers

PMID41167676
PMCPMC12588242

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.