Evidence map›Paper›PMID 41167656›Full record

ArticleIn vivo (Athens, Greece)

Exploring the Genetic Role of Matrix Metalloproteinase-13 Variants in Pterygium Risk.

Hung-Chih Chen, Ning-Yi Hsia, Pei-Shin Hu, Te-Chun Hsia, Yun-Chi Wang, Hou-Yu Shih, Wen-Shin Chang, DA-Tian Bau, Chia-Wen Tsai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Revealing the Association ofIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hung-Chih Chen *Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Ning-Yi Hsia *Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Pei-Shin Hu *Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Te-Chun HsiaTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Yun-Chi WangGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Hou-Yu ShihGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
Wen-Shin ChangGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
DA-Tian BauGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; 013280@tool.caaumed.org.tw.
Chia-Wen TsaiGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.; 017891@tool.caaumed.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPterygium is a common ocular surface disorder characterized by abnormal fibrovascular growth and extracellular matrix remodeling, yet its precise molecular etiology remains unclear. Matrix metalloproteinases (MMPs) have been implicated in pterygium pathogenesis. However, the genetic contribution of MATERIALS AND

methodsThis case-control study evaluated the association between

resultsThe genotypic distributions of

conclusionThese findings suggest that

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseMatrix Metalloproteinase 13Polymorphism, Single NucleotidePterygiumAdultAgedAllelesCase-Control StudiesFemaleGene FrequencyGenotypeHumansMaleMiddle AgedOdds RatioMatrix Metalloproteinase 13MMP13 protein, humanAgegenotypematrix metalloproteinase-13polymorphismpterygiumsexTaiwan

Identifiers

PMID41167656
PMCPMC12588207

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.