Evidence map›Paper›PMID 41167634›Full record

ArticleRMD open2025

Joint involvement in VEXAS and non-VEXAS clonal haematopoiesis: two clusters from a multicentre regional cohort.

Baptiste de Maleprade, Fabien Jastrzebski, Ygal Benhamou, Gaetan Sauvetre, Benjamin Membrey, Marine Avenel, Alexandre Curie, Guillaume Armengol, Pauline Brevet, Vincent Langlois and 4 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in RMD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Baptiste de MalepradeDepartment of Rheumatology, University Hospital Centre Rouen, Rouen, Normandy, France baptistedemaleprade@gmail.com.ORCID 0009-0000-0687-0435
Fabien JastrzebskiDepartment of Rheumatology, University Hospital Centre Rouen, Rouen, Normandy, France.
Ygal BenhamouDepartment of Internal Medicine, University Hospital Centre Rouen, Rouen, Normandy, France.
Gaetan SauvetreDepartment of Internal Medicine, University Hospital Centre Rouen, Rouen, Normandy, France.
Benjamin MembreyDepartment of Internal Medicine, Hospital Centre Dieppe, Dieppe, Normandy, France.
Marine AvenelDepartment of Internal Medicine, Intercommunal Hospital Centre Elbeuf-Louviers-Val de Reuil Elbeuf-Les Feugrais Site, Saint-Aubin-lès-Elbeuf, Normandy, France.
Alexandre CurieDepartment of Internal Medicine, CH Eure-Seine, Évreux, Normandy, France.
Guillaume ArmengolDepartment of Internal Medicine, Saint Hilaire Clinic, Rouen, France.
Pauline BrevetDepartment of Rheumatology, University Hospital Centre Rouen, Rouen, Normandy, France.
Vincent LangloisDepartment of Internal Medicine, Groupe Hospitalier du Havre, Le Havre, Normandy, France.
Thierry LequerreDepartment of Rheumatology, University Hospital Centre Rouen, Rouen, Normandy, France.
Aspasia Stamatoullas-BastardDepartment of Hematology, Centre Henri Becquerel, Rouen, France.
Fabrice JardinDepartment of Hematology, Centre Henri Becquerel, Rouen, France.
Olivier VittecoqDepartment of Rheumatology, University Hospital Centre Rouen, Rouen, Normandy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the joint manifestations associated with clonal haematopoiesis and to compare patients with and without VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome.

methodsPatients screened for

resultsThirty patients with a haematological disorder associated with dysimmune manifestations were included: 17 (57%) without

conclusionJoint involvement was more frequent in patients with clonal haematopoiesis and dysimmune manifestations unrelated to VEXAS syndrome.

Indexed as

Clonal HematopoiesisUbiquitin-Activating EnzymesAdolescentAdultAgedFemaleFranceHumansMaleMiddle AgedMutationMyelodysplastic SyndromesRetrospective StudiesSkin Diseases, GeneticYoung AdultUBA1 protein, humanUbiquitin-Activating EnzymesArthritisHematologyInflammation

Identifiers

PMID41167634
PMCPMC12574337

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.