Evidence map›Paper›PMID 41166533›Full record

SynthesisPsychotherapy and psychosomatics2026

What Helps and Hinders Recovery from Depression? A Systematic Review and Qualitative Evidence Synthesis of Patient-Identified Recovery Factors.

David Wedema, Johanna H M Hovenkamp-Hermelink, Eliza L Korevaar, Klaas J Wardenaar, Robert A Schoevers

Abstract readSystematic Review
In one paragraph

Synthesis in Psychotherapy and psychosomatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David WedemaDepartment of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, d.wedema@umcg.nl.
Johanna H M Hovenkamp-HermelinkDepartment of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Eliza L KorevaarResearch and Innovation Center for Rehabilitation, Hanze University of Applied Sciences, Groningen, The Netherlands.
Klaas J WardenaarDepartment of Child and Family Welfare, University of Groningen, Faculty of Behavioural and Social Sciences, Groningen, The Netherlands.
Robert A SchoeversDepartment of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Depression is a common mental disorder with often persistent consequences. Even after adequate treatment, recovery may be far from optimal. To enhance outcomes, we aimed to identify and synthesize factors that depressed adults themselves perceived as facilitating or hindering recovery.

methodsWe searched PubMed, PsycINFO, and SocINDEX (last search: February 2, 2025), screened reference lists, and consulted experts. Eligible studies used a qualitative design, published in English or Dutch since 1980, and explored recovery factors in adults (≥18 years) with depression.

resultsFrom 4,872 records, 3,394 were screened on title and abstract, and 122 on full text. Twenty-seven articles were eligible and included in the qualitative evidence synthesis. These articles described the experiences with recovery from depression of 939 individuals. Most studies were conducted in Europe (N = 11), followed by North America (N = 7), Asia (N = 6), Australia (N = 5), and South America (N = 2). Eight overarching themes emerged: (1) social connections, (2) reconstructing the self, (3) autonomy, (4) professional support, (5) self-management strategies, (6) physical health, (7) instrumental facilitators/barriers, and (8) temporal dimensions. We present an overview of the relative importance of factors and propose a conceptual model illustrating the interconnectedness of themes.

conclusionRecovery from depression involves a diverse range of interconnected factors. While professional treatment is considered valuable, various other factors also influence individuals' recovery. Our findings underscore the need for an integrated and person-centred approach that combines therapeutic support with personal capacities, self-management strategies, and contextual aspects, emphasizing relational quality, self-reflection, and open dialogue, to optimize subjectively experienced recovery. </p>.

Indexed as

Depressive DisorderSocial SupportAdultHumansPersonal AutonomyQualitative ResearchDepressionMechanisms of changeQualitative researchRecovery

Identifiers

PMID41166533
PMCPMC12707877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.