Evidence map›Paper›PMID 41166525›Full record

ArticleJMIR formative research2025

Behavior Emotion Therapy System and You: Co-Design and Evaluation of a Mental Health Chatbot and Digital Human for Mild to Moderate Anxiety in Healthy Participants.

Almira Osmanovic Thunström, Lilas Ali, Hanne Krage Carlsen, Maria Bohm, Linda Wesén, Olof Wrede, Iris Sarajlic Vukovic, Andreas Hellström, Tomas Larson, Steinn Steingrimsson

Abstract read
In one paragraph

Article in JMIR formative research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Almira Osmanovic ThunströmInstitute of Neuroscience and Physiology, Gothenburg University, Journalvägen 5, Gothenburg, 41560, Sweden.ORCID 0000-0002-8791-9524
Lilas AliPsychiatric Department, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.ORCID 0000-0001-7027-4371
Hanne Krage CarlsenCentre of Registers Västra Götaland, Gothenburg, Sweden.ORCID 0000-0003-1656-9624
Maria Bohm
Linda WesénPsychiatric Department, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.ORCID 0009-0007-8457-2231
Olof WredeCrisis and Trauma Center, Regionshälsan, Region Västra Götaland, Gothenburg, Sweden.ORCID 0000-0003-2612-7424
Iris Sarajlic VukovicPsychiatric Department, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.ORCID 0000-0002-4803-1979
Andreas HellströmDepartment of Technology Management and Economics, Chalmers University of Technology, Gothenburg, Sweden.ORCID 0000-0002-7484-8632
Tomas LarsonPsychiatric Department, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.ORCID 0000-0002-7271-7604
Steinn SteingrimssonPsychiatric Department, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.ORCID 0000-0001-8320-5607

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Co-design is a collaborative approach involving end users, stakeholders, and designers in creating digital tools for health care. This study focuses on the co-design and evaluation of Behavior, Emotion, Therapy System, and You (BETSY), a mental health chatbot and digital human for mild to moderate anxiety. Objective: This study aims to develop and evaluate BETSY through a co-design process involving potential users. Methods: The study used a mixed-methods approach across 3 phases. Phase 1 involved recruiting 87 volunteer participants through social media for initial end-user requirements. Phase 2 focused on the design process based on end-user requirements using the expertise of 10 stakeholders in health care and health service user. Phase 3 evaluated the 2 prototyped interfaces (a text-only chatbot and a voice-activated digital human chatbot) with 45 healthy volunteers. Results: For phase 1, 61% (n=51) of participants had previous experience with chatbots and 86% expressed a willingness or potential willingness to use a chatbot for mental health support. Thematic analysis in phase 2 revealed key user preferences for a personalized, nonjudgmental chatbot with a clear identity and a focus on empathy. Privacy concerns and the need for clear interaction guidelines were highlighted. In phase 3, the users showed a strong preference for discussing anxiety related to work, relationships, and health. Both text-only and voice-activated digital human users considered BETSY valuable for managing mild to moderate anxiety and providing self-help exercises. Conclusions: The co-design process yielded valuable insights for developing BETSY. While users recognized its potential as an accessible first step before seeking professional help, they also identified areas for improvement, including more nuanced conversation capabilities and a broader range of exercises. BETSY's potential as a screening tool for health care was consistently acknowledged, suggesting its capability for alleviation of health care system burdens.

Indexed as

AnxietyBehavior TherapySocial MediaAdultEmotionsFemaleGenerative Artificial IntelligenceHealthy VolunteersHumansMaleMiddle AgedYoung Adultanxietyavatarbehavior emotion therapy system and youBETSYchatbotchatbotsco-designconversational agentdigital healthdigital humanhealthcaremental healthmental health supportmixed-methodmixed-methodsprototypingself-helpsocial media

Identifiers

PMID41166525
PMCPMC12574741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.