Evidence map›Paper›PMID 41166504›Full record

ArticleAustralasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists2026

Are cognitive deficits more severe among people with treatment-resistant schizophrenia than treatment responders?

Ananthakrishnan Koloth, Kim Yeak, Somayyeh Azimi, Radhakrishnan Koloth, Aneeka Alexander, Milan Dragovic, Alexander Panickacheril John

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PubMed Full text at PMC Publisher
In one paragraph

Article in Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ananthakrishnan KolothSir Charles Gairdner Hospital, North Metropolitan Health Service, Perth, WA, Australia.
Kim YeakBentley Health Service, Bentley, WA, Australia.
Somayyeh AzimiClinical Research Centre, North Metropolitan Health Service Mental Health, Perth, WA, Australia.
Radhakrishnan KolothPeel and Rockingham Kwinana Health Service, Perth, WA, Australia.
Aneeka AlexanderNorthern Beaches Hospital, Sydney, NSW, Australia.
Milan DragovicClinical Research Centre, North Metropolitan Health Service Mental Health, Perth, WA, Australia.ORCID 0000-0003-2604-0230
Alexander Panickacheril JohnBentley Health Service, Bentley, WA, Australia; and Medical School, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0002-1989-6578

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundGiven the robust association of cognitive deficits (CD) with community functioning in people with schizophrenia and the inconsistent findings from the limited research on CD among people with treatment-resistant schizophrenia (TRS), we evaluated the neurocognitive functions of patients with TRS.MethodsWe retrospectively collated data on cognition and selected demographic and clinical variables of 181 patients with TRS and 59 with treatment-responsive schizophrenia (non-TRS) admitted to a psychiatric rehabilitation facility from 2010 to 2019. The Brief Assessment of Cognition in Schizophrenia (BACS) was used to evaluate cognitive function. Multivariate analysis was utilised to compare the BACS scores of the two groups.ResultsTRS patients had more severe CD than non-TRS patients, with the BACS composite score (

Indexed as

Antipsychotic AgentsCognitive DysfunctionSchizophreniaSchizophrenia, Treatment-ResistantAdultClozapineFemaleHumansMaleMiddle AgedNeuropsychological TestsRetrospective StudiesSeverity of Illness IndexAntipsychotic AgentsClozapineclozapinecognition in psychosiscognitive deficitsschizophreniatreatment resistance

Identifiers

PMID41166504
PMCPMC13062446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.