Evidence map›Paper›PMID 41166365›Full record

ArticlePLoS biology2025

Better understanding of laboratory animal genetics will improve reproducibility.

Guillaume Pavlovic, Sara Wells, Yann Hérault, Lydia Teboul

Abstract read
In one paragraph

Article in PLoS biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guillaume PavlovicPHENOMIN-Institut Clinique de la Souris, CELPHEDIA, CNRS, INSERM, Université de Strasbourg, Illkirch-Graffenstaden, France.ORCID 0000-0001-9122-4592
Sara WellsThe Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, United Kingdom.
Yann HéraultPHENOMIN-Institut Clinique de la Souris, CELPHEDIA, CNRS, INSERM, Université de Strasbourg, Illkirch-Graffenstaden, France.
Lydia TeboulThe Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, United Kingdom.ORCID 0000-0002-2789-8637

Funding

UKRI/MRC MC_UP_2201/1UKRI/MRC MC_UP_2201/2UKRI/MRC MC_UP_2201/3
6 · The paper itself

Abstract

Inconsistent characterization and reporting of laboratory animal genetics undermine research quality and reproducibility. We need to recognize the value of genetic characterization, improve training for researchers, and implement rigorous reporting standards.

Indexed as

Animals, LaboratoryAnimalsReproducibility of ResultsResearch Design

Identifiers

PMID41166365
PMCPMC12588450

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.