Evidence map›Paper›PMID 41166154›Full record

ArticleNucleic acids research2026

ViMIC 2.0: an updated database of human disease-related viral mutations, integration sites, and multi-omics data.

Chenjun Huang, Honglian Huang, Min Ding, Jiawen Zhu, Xin Qin, Zeyuan Zhang, Xiaoyang Zhao, Ziyi Wei, Min Wang, M James C Crabbe and 2 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chenjun HuangDepartment of Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Honglian HuangSchool of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
Min DingDepartment of Interventional Oncology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
Jiawen ZhuDepartment of Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Xin QinDepartment of Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Zeyuan ZhangDepartment of Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.
Xiaoyang ZhaoThe First Dispatched Outpatient Department, 905th Hospital of PLA Navy, Shanghai 200052, China.
Ziyi WeiSchool of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
Min WangDepartment of Laboratory Medicine, Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China.
M James C CrabbeWolfson College, Oxford University, Oxford OX12JD, United Kingdom.
Xiaoyan ZhangSchool of Life Sciences and Technology, Tongji University, Shanghai 200092, China.ORCID 0000-0003-1562-0045
Ying WangDepartment of Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.ORCID 0000-0002-1819-294X

Funding

National Natural Science Foundation of China 32370694National Natural Science Foundation of China 81972914)Shanghai Municipal Health Commission 2024GKM25
6 · The paper itself

Abstract

ViMIC 2.0 is an updated database that provides comprehensively curated data on virus mutations (VMs), viral integration sites (VISs), and multi-omics datasets related to human diseases. Leveraging expanding public data, ViMIC 2.0 significantly enhanced data scale, diversity, and analytical capabilities compared to the previous version. In terms of data volume, the number of virus types has increased from 8 to 28, VM entries have grown from 31 712 to 64 168, virus-related diseases expanded from 77 to 177, literature rose from 2539 to 6433, and omics datasets have substantially increased from 28 sets of single expression profile data to 255 sets of multi-omics data. In addition, ViMIC 2.0 has updated 9409 VISs, 173 048 sequences, newly incorporated sequencing types such as single-cell transcriptomic sequencing (scRNA-seq), and genome binding/occupancy profiling. Regarding the visualization module, ViMIC 2.0 now provides results of differential gene expression analysis for bulk RNA-seq or array, cell type annotation and gene feature plot for scRNA-seq data, and differential methylation analysis for methylation profiling, as well as peak annotation for ChIP-seq/ChIP-on-chip/ATAC-seq data. In summary, ViMIC 2.0 serves as a user-friendly, up-to-date, and well-maintained resource for the virology research community. ViMIC 2.0 is freely accessible at http://www.biomedinfo.cn/ViMIC2.0/index.php.

Indexed as

Databases, GeneticMutationVirus DiseasesVirusesVirus IntegrationGenomicsHumansMultiomicsSoftwareUser-Computer Interface

Identifiers

PMID41166154
PMCPMC12807604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.