ArticleMolecular biomedicine2025
Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression.
Article in Molecular biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Curcumin analogue FLLL32 induces ferroptosis by targeting the STAT3-GPX4/SLC40A1 axis in colorectal cancer.Molecular biomedicine · 2026Article
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Authors and funding
10 authors.
Funding
Abstract
Colorectal cancer (CRC) is a common malignant tumor of the digestive tract, and chemotherapy resistance along with adverse reactions during treatment present significant challenges in clinical practice. Therefore, there is an urgent need to find effective and low-toxicity therapeutic agents. Ferroptosis, a recently discovered form of cell death, has attracted attention as a potential new cancer treatment strategy. Microwave dynamic therapy (MWDT), as a promising anticancer agent, has been shown to significantly inhibit various malignancies, including CRC. However, the role of MWDT in ferroptosis and its underlying mechanisms have not been fully explored. In this study, we demonstrated that MWDT treatment significantly increased levels of lipid peroxidation (LPO), reactive oxygen species (ROS), malondialdehyde (MDA), and Fe
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