Evidence map›Paper›PMID 41166015›Full record

ArticleNeuroinformatics2025

Workflow for the Creation of 3D Stereoscopic Models of Supra- and Infratentorial Brain Venous Anatomy and their Integration in a Virtual Reality Environment.

Francesco Carbone, Toma Spiriev, Martin Trandzhiev, Michael Wolf-Vollenbröker, Kay M Körner, Andrea Steuwe, Matteo de Notaris, Vladimir Nakov, Jan F Cornelius

Abstract read
PubMed Publisher
In one paragraph

Article in Neuroinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco CarboneDepartment of Neurosurgery, Karlsruher Neurozentrum, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany.ORCID http://orcid.org/0000-0002-6351-9999
Toma SpirievDepartment of Neurosurgery, Acibadem City Clinic, University Hospital Tokuda, Bul. Nikola Vaptsarov 51B, Sofia, 1407, Bulgaria. spiriev@gmail.com.
Martin TrandzhievDepartment of Neurosurgery, Acibadem City Clinic, University Hospital Tokuda, Bul. Nikola Vaptsarov 51B, Sofia, 1407, Bulgaria.
Michael Wolf-VollenbrökerInstitute for Anatomy I, Medical Faculty & University Hospital Düsseldorf, Heinrich- Heine-University, Düsseldorf, Germany.
Kay M KörnerInstitute for Anatomy I, Medical Faculty & University Hospital Düsseldorf, Heinrich- Heine-University, Düsseldorf, Germany.
Andrea SteuweDepartment of Diagnostic and Interventional Radiology, Medical Faculty & University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Matteo de NotarisUnit of Neurosurgery, University Hospital San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy.
Vladimir NakovDepartment of Neurosurgery, Acibadem City Clinic, University Hospital Tokuda, Bul. Nikola Vaptsarov 51B, Sofia, 1407, Bulgaria.
Jan F CorneliusDepartment of Neurosurgery, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent advance in technology allows for the photorealistic digitalization of anatomical specimens that can now be presented through various dynamic visualization modalities, enabling a more interactive learning experience. This study explores a comprehensive workflow for reproducibly integrating photorealistic three-dimensional (3D) anatomical scans of the supra- and infratentorial venous system with stereoscopic visualization and virtual reality (VR) for anatomical learning. A formaldehyde-fixed head and neck specimen was injected with radiopaque dye into its vessels, and a post-mortem computed tomography (CT) venography was performed. A layered anatomical dissection of the intracranial venous system was performed. Photogrammetry surface scanning was employed to create 3D anatomical models, which were then post-processed to produce stereoscopic 3D images and videos using open-source software. In addition, the 3D models were formatted for immersive VR environment integration. Six photorealistic surface models and one CT venography-based reconstruction were generated. These were incorporated into several platforms: multiplayer VR environment using stand-alone headsets, and stereoscopic materials suitable for phone-based VR viewers, 3D multimedia projectors, or 3D monitors with passive or active glasses. These formats supported multiple learning scenarios (VR in single or multiplayer sessions), 3D stereoscopic lectures using 3D multimedia, real-time 3D stereoscopic visualization, or prerecorded videos for phone-based VR visualization. Building on these formats, the proposed workflow enables a realistic and spatially accurate representation of the anatomical data with photorealistic 3D models and facilitates the creation of accessible educational content for 3D stereoscopic presentations and immersive dedicated VR sessions, all through a user-friendly technical approach.

Indexed as

BrainCerebral VeinsImaging, Three-DimensionalModels, AnatomicVirtual RealityWorkflowHumansTomography, X-Ray ComputedIntracranial veinsNeuroanatomyPhotogrammetryStereoscopyThree-dimensional modelsVirtual reality

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.