Evidence map›Paper›PMID 41166004›Full record

ArticleProgress in orthodontics2025

Force comparison between Perfitalign 4D aligners and thermoformed aligners for mandibular incisor retraction: an in vitro study.

Jianing Xu, Yanning Ma, Ruyue Qiang, Xinyue Fan, Mingxin Zhang, Zuolin Jin

Abstract readComparative Study
In one paragraph

Article in Progress in orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianing XuSchool of Stomatology, Air Force Medical University, Xi'an, China.
Yanning MaShanxi Medical University School and Hospital of Stomatology, Taiyuan, China.
Ruyue QiangCollege of Stomatology, Xi'an Jiaotong University, Xi'an, China.
Xinyue FanSchool of Stomatology, Air Force Medical University, Xi'an, China.
Mingxin ZhangStomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, China.
Zuolin JinStomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, China. zuolinj@163.com.

Funding

Key Project of the Shaanxi Provincial Key Research and Development Program 2024SF-GJHX-37New Technologies and New Business of School of Stomatology, Air Force Medical University Fund LX-2023-102,LX2022-306,LX2021-204The National Clinical Research Center for Oral Diseases LCA202202, LCB202202The National Natural Science Foundation of China 8240036014
6 · The paper itself

Abstract

objectivesTo quantitatively compare the orthodontic forces exerted during mandibular incisor retraction by Perfitalign 4D aligners and thermoformed aligners over a 60-hour dynamic monitoring period, assess tooth movement trends, and investigate the effects of shape-memory properties on force characteristics. MATERIALS AND

methodsThree groups of aligners were designed for mandibular incisor retraction. Group A aligners were fabricated using Erkodur foils (ERKODENT Erich Kopp) via thermoforming, while Groups B and C were fabricated using DCA resin (LuxCreo) via 3D printing. Groups A and B possessed a step size of 0.15 mm, whereas group C had a step size of 0.20 mm. Force data were monitored on a mandibular model for 60 h using a multi-axis transducer at 4-hour wear intervals. Groups B and C underwent thermal reactivation after every 12 h of cumulative wear, with recordings taken immediately before and after each activation.

resultsAll groups exhibited high repeatability (ICC > 0.9). Perfitalign 4D aligners exhibited significant force recovery after thermal reactivation, though the recovery degree slightly decreased with repeated activations. Vertical forces markedly fluctuated but increased after thermal reactivation. Intergroup comparisons revealed significantly lower lingual forces in groups B/C compared to group A (P < 0.05). For mesiodistal and vertical directions, forces in groups B/C showed no significant reductions compared to group A. Residual stress analysis revealed rapid initial decay in group A, which decelerated subsequently, while groups B and C exhibited cyclic characteristics of "decay-thermal reactivation-induced recovery-decay". At 0 h, moment-to-force ratios (Mx/Fy) for mandibular incisors were significantly lower in groups B/C (- 3.3 to - 8.7 mm) than in group A (- 8.0 to - 10.7 mm).

conclusionPerfitalign 4D aligners enable cyclic force recovery via shape-memory properties, independent of step size (0.15/0.20 mm). Despite larger steps, their lingual forces remained significantly lower than those of thermoformed aligners. A trend closer to bodily movement was observed with Perfitalign 4D aligners, although clinical studies are needed to validate movement efficiency and the long-term effects of elevated mesiodistal/vertical forces.

Indexed as

IncisorOrthodontic Appliance DesignOrthodontic Appliances, RemovableTooth Movement TechniquesDental Stress AnalysisHumansIn Vitro TechniquesMandiblePrinting, Three-DimensionalStress, Mechanical3D-printed aligners4D alignersClear alignersForceRetraction

Identifiers

PMID41166004
PMCPMC12575893

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.