Synthetic Apomeiosis in Tomato via the Mutagenesis of SlSPO11-1, SlREC8, and SlTAM to Engineer Mitosis Instead of Meiosis.

Yazhong Wang, Iris E Zahn, Bas Heidemann, Roven Rommel Fuentes, Charles J Underwood

Abstract read

In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Breeding better crops: lessons from the homologous recombination pathway.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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5 · Who and what money

Authors and funding

5 authors.

Yazhong WangDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding Research, Cologne, Germany.

Iris E ZahnDepartment of Plant & Animal Biology, Radboud Institute for Biological and Environmental Sciences, Radboud University, Nijmegen, The Netherlands.

Bas HeidemannDepartment of Plant & Animal Biology, Radboud Institute for Biological and Environmental Sciences, Radboud University, Nijmegen, The Netherlands.

Roven Rommel FuentesDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding Research, Cologne, Germany.

Charles J UnderwoodDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding Research, Cologne, Germany. charles.underwood@ru.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterosis, or hybrid vigor, is a crucial driver of yield and robustness in modern hybrid breeding. However, F1 hybrid plants give rise to genetically variable F2 offspring due to the segregation of genetic material in male and female meiosis. Bioengineered clonal gametes, containing identical genetic material as the parental plant, offer an innovative route to maintain genetic heterozygosity as a component of synthetic apomixis, or as a tool in breeding to carry out polyploid genome design. In this protocol, we present methods to generate clonal gametes in hybrid tomato plants by inducing synthetic apomeiosis through the Mitosis instead of Meiosis (MiMe) system. This protocol can be used to implement MiMe in tomato plants of choice, and describes the methods for comprehensive assessment of plant fertility and ploidy.

Indexed as

ApomixisMeiosisMitosisMutagenesisPlant ProteinsSolanum lycopersicumPlant BreedingPlant ProteinsApomeiosisApomixisClonal gametesMeiosisMitosis instead of Meiosis (MiMe)Plant hybridizationPloidyTomato

Identifiers

PMID41165988

DOI10.1016/j.ncrops.2023.10.001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.