Evidence map›Paper›PMID 41165943›Full record

ArticleWorld journal of microbiology & biotechnology2025

Encapsulation of Saccharomyces boulardii into sugar pellets coated with an enteric polymer.

Karla Lilian Bailon-Barceinas, Zacnite Sánchez-Portilla, Alma Delia Román-Gutiérrez, Luz María Melgoza-Contreras, Raquel González-Vázquez, Lino Mayorga-Reyes, María Angélica Gutiérrez-Nava

Abstract read
In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karla Lilian Bailon-BarceinasMaestria en Ciencias Farmaceuticas, Departamento de Sistemas Biologicos, Universidad Autonoma Metropolitana, Unidad Xochimilco, Ciudad de Mexico, 04960, Mexico.
Zacnite Sánchez-PortillaDoctorado en Ciencias Biologicas y de la Salud, Universidad Autonoma Metropolitana, Unidad Xochimilco, Ciudad de Mexico, 04960, Mexico.ORCID http://orcid.org/0000-0001-6554-7574
Alma Delia Román-GutiérrezArea Academica de Quimica, Universidad Autonoma del Estado de Hidalgo, Ciudad del Conocimiento, Carretera Pachuca- Tulancingo Km 4.5s/n, Mineral de la Reforma, Hidalgo, 42184, Mexico.ORCID http://orcid.org/0000-0003-0927-1061
Luz María Melgoza-ContrerasLaboratorio de Farmacotecnia, Departamento de Sistemas Biologicos, Universidad Autonoma Metropolitana, Unidad Xochimilco, Ciudad de Mexico, 04960, Mexico.ORCID http://orcid.org/0000-0001-5509-6415
Raquel González-VázquezLaboratorio de Biotecnologia, Departamento de Sistemas Biologicos, SECIHTI-Universidad Autonoma Metropolitana, Unidad Xochimilco, Ciudad de Mexico, 04960, Mexico. rgonzalezv@correo.xoc.uam.mx.ORCID http://orcid.org/0000-0003-4400-7506
Lino Mayorga-ReyesLaboratorio de Biotecnologia, Departamento de Sistemas Biologicos, Universidad Autonoma Metropolitana, Unidad Xochimilco, Ciudad de Mexico, 04960, Mexico.ORCID http://orcid.org/0000-0003-1257-7897
María Angélica Gutiérrez-NavaLaboratorio de Ecologia Microbiana, Departamento de Sistemas Biologicos, Universidad Autonoma Metropolitana, Unidad Xochimilco, Ciudad de Mexico, 04960, Mexico. agutz@correo.xoc.uam.mx.ORCID http://orcid.org/0000-0001-6342-5549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many current probiotic products do not optimally release enough viable cells at the site of action due to the loss of viability during manufacturing and passage through the stomach. This work aimed to formulate a modified release system that protects S. boulardii during the manufacturing process and under simulated acidic gastric conditions. S. boulardii was layered to sugar pellets, coated at 5% and 10% with the enteric polymer Eudragit

Indexed as

PolymersProbioticsSaccharomyces boulardiiSugarsCapsulesDrug CompoundingGelatinHydrogen-Ion ConcentrationMicrobial ViabilityPolymethacrylic AcidsCapsulesGelatinmethylmethacrylate-methacrylic acid copolymerPolymersPolymethacrylic AcidsSugarsEncapsulationEudragit ® S12.5Intestinal deliveryModified release systemSaccharomyces boulardii

Identifiers

PMID41165943
PMCPMC12575462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.