Evidence map›Paper›PMID 41165820›Full record

SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Comparing ventricular access devices and ventriculosubgaleal shunts for posthemorrhagic ventricular dilatation: systematic review and meta-analysis.

Raniah Aljeaid, Mohamed Abdelmawla, Maan Abu Zaid, Asma Almazrooei, Nisreen Kafi, Soha Alomar

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Bedside external ventricular drainage in the NICU: procedural efficiency and infection trends in a 15-year single-center cohort.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raniah AljeaidPediatric Department, King Fahad Armed Forces Hospital, NICU Division, Ministry of Defense Health Services, Jeddah, Saudi Arabia. raniah.aljeaid@gmail.com.ORCID 0009-0003-8312-4227
Mohamed AbdelmawlaPediatric Department, King Fahad Armed Forces Hospital, NICU Division, Ministry of Defense Health Services, Jeddah, Saudi Arabia.ORCID 0000-0002-7861-2440
Maan Abu ZaidPediatric Department, King Fahad Armed Forces Hospital, NICU Division, Ministry of Defense Health Services, Jeddah, Saudi Arabia.
Asma AlmazrooeiPediatric Department, King Fahad Armed Forces Hospital, NICU Division, Ministry of Defense Health Services, Jeddah, Saudi Arabia.
Nisreen KafiPediatric Department, King Fahad Armed Forces Hospital, NICU Division, Ministry of Defense Health Services, Jeddah, Saudi Arabia.
Soha AlomarDivision of Neurosurgery, Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0001-5996-6764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe complications of severe intraventricular hemorrhage (IVH), such as posthemorrhagic ventricular dilatation (PHVD) or posthemorrhagic hydrocephalus (PHH), affect 25-80% of infants with this condition. These conditions increase morbidity, mortality, and long-term neurodevelopmental outcomes. Ventricular access devices (VADs) and ventriculosubgaleal shunts (VSGSs) are temporary cerebrospinal fluid diversion methods for PHVD management. The aim of this study was to compare the effectiveness of VADs and VSGSs in reducing PHVD-related complications.

methodsA comprehensive search through the Ovid interface was conducted, including Embase (1974 to October 9, 2023), the Cochrane Central Register of Controlled Trials, CENTRAL (September 2023), and Ovid MEDLINE (1946 to October 9, 2023). All randomized controlled trials (RCTs) and nonrandomized studies comparing VADs and VSGSs, and peer-reviewed published original research, were selected. Meta-analyses were performed using a fixed-effects model and the Mantel‒Haenszel method.

resultsSix observational studies (one prospective cohort and five retrospective cohorts) with a total of 497 infants were included, and no RCTs were found. For the primary outcome (permanent shunt insertion), a meta-analysis of six observational studies revealed no difference in intervention benefit (RR 1.02, 95% CI 0.91 to 1.14). VADs had little to no effect on mortality (two studies: RR 0.56, 95% CI 0.25 to 1.26), CSF infection (five studies: RR 1.24, 95% CI 0.72 to 2.11) or CSF leakage (two studies: RR 0.64, 95% CI 0.14 to 2.86).

conclusionsThe evidence regarding VAD or VSGS use for infants with PHVD is limited to observational studies. Thus, the effects of VADs on PHVD-related complications are very uncertain. High-quality RCTs are needed to determine the optimal temporizing device for high-risk preterm infants with PHVD.

Indexed as

Cerebral HemorrhageCerebral VentriclesCerebrospinal Fluid ShuntsHydrocephalusDilatation, PathologicHumansInfantInterventricular hemorrhagePosthemorrhagic hydrocephalusPosthemorrhagic ventricular dilatationVentricular access deviceVentriculosubgaleal shunt

Identifiers

PMID41165820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.