Evidence map›Paper›PMID 41165819›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Relation of pulmonary diffusing capacity changes to HRCT chest and V/Q SPECT findings at short-term and intermediate follow-up after COVID-19: a prospective cohort study (The secure study).

Thora Wesenberg Helt, Rie Skovly Thomsen, Jan Christensen, Thomas Kromann Lund, Anna Kalhauge, Frederikke Rönsholt, Daria Podlekavera, Elisabeth Arndal, Anne-Mette Lebech, Ronan M G Berg and 2 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thora Wesenberg HeltDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark.ORCID 0000-0002-3763-8839
Rie Skovly ThomsenCentre for Physical Activity Research, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-3858-3056
Jan ChristensenDepartment of Occupational Therapy and Physiotherapy, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-1114-7465
Thomas Kromann LundDepartment of Cardiology, Section for Lung Transplantation, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-8987-3136
Anna KalhaugeDepartment of Radiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-2420-7896
Frederikke RönsholtDepartment of Cardiology, Section for Lung Transplantation, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-1170-5896
Daria PodlekaveraDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Elisabeth ArndalDepartment of Otorhinolaryngology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0001-7858-5684
Anne-Mette LebechDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-0943-3289
Ronan M G BergDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark. ronan@sund.ku.dk.ORCID 0000-0002-5757-9506
Terese L KatzensteinDepartment of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-2233-500X
Jann MortensenDepartment of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark.ORCID 0000-0002-1399-8995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral patients exhibit a severity-dependent reduced pulmonary diffusing capacity (D

methodsA total of 153 patients diagnosed with COVID-19 between March 2020 and March 2021 were included in the study. The patients underwent lung function testing, chest HRCT, and V/Q SPECT at short-term (5.6 months) follow-up. Individuals exhibiting any evidence of post-COVID-19 sequelae (n = 121) were also referred to intermediate follow-up (12.5 months).

resultsAt short-term follow-up, a severity dependent reduction in D

conclusionThe severity-dependent reduction in D

Indexed as

COVID-19LungPulmonary Diffusing CapacityTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesTime FactorsCOVID-19Long COVIDPulmonary diffusing capacitySARS-CoV-2

Identifiers

PMID41165819
PMCPMC12860846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.