Observational studyEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025
Pediatric moderate and severe traumatic brain injury - A national, population-based cohort study.
Observational study in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Inflammatory-neurodegenerative crosstalk in pediatric severe traumatic brain injury: a multi-domain plasma proteomic study.Molecular medicine (Cambridge, Mass.) · 2026Article
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4 authors.
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Abstract
purposeThis study aims to investigate the epidemiological characteristics, injury mechanisms, and clinical outcomes of children with moderate and severe traumatic brain injury (TBI), using population-based data from a national trauma registry.
methodsThis nationwide observational cohort study includes all pediatric patients (0-17 years) with moderate and severe TBI registered in the Norwegian Trauma Registry between January 1, 2017, and December 31, 2020.
resultsA total of 348 pediatric patients with moderate (n = 289, 83%) and severe n = 59, 17%) TBI were analyzed. The most common injury mechanism were high-energy falls (33%) and road traffic accidents (29%). The 30-day mortality rate was 3%, significantly higher in severe TBI (12%) than moderate TBI (1%, p < 0,001). Patients with severe TBI had longer hospital stays and poorer functional recovery than those with moderate TBI.
conclusionThis population-based study on pediatric TBI patients over a period of 4 years revealed a relatively low mortality rate. In 4 out of 5 patients moderate or severe TBI resulted in a good outcome with moderate, low or no disability. Advancing the understanding of evidence-based interventions aiming at preventing both primary and secondary injuries associated with pediatric TBI is essential for optimizing recovery and promoting functional independence in these young patients.
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