Evidence map›Paper›PMID 41165755›Full record

ReviewKidney3602026

Design and Implementation of a Universal Donor Kidney.

William H Fissell, Shuvo Roy

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Kidney360, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William H FissellNephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-3960-3998
Shuvo RoyBioengineering and Therapeutic Sciences, University of California, San Francisco, California.ORCID 0000-0002-3236-6336

Funding

Building an Implantable Artificial KidneyU01EB021214 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FISSELL, WILLIAM H, ROY, SHUVO · 2015 to 2018
$6.0M
Miniaturized Implantable Renal Assist Device for Total Renal Replacement TherapyR01EB008049 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROY, SHUVO · 2007 to 2009
$3.1M
Biocompatibility of Implantable Renal Replacement DevicesR01EB014315 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROY, SHUVO · 2012 to 2015
$2.3M
BioMEMS Model of Glomerular FunctionK08EB003468 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FISSELL, WILLIAM H · 2004 to 2008
$952k
BioMEMS Materials for Renal Tissue EngineeringR21EB002285 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FISSELL, WILLIAM H · 2003 to 2004
$316k
NIBIB NIH HHS K08EB003468NIBIB NIH HHS R01EB008049NIBIB NIH HHS R01EB014315NIBIB NIH HHS R21EB002285NIBIB NIH HHS U01EB021214
6 · The paper itself

Abstract

The mismatch between demand for donor kidneys and available supply continues to grow despite better treatment of kidney disease and innovative efforts to expand the supply of human donors. Stem cell and xenograft technologies are exciting, but scientific challenges remain. We developed a hybrid device composed of silicon nanopore membranes and living kidney cells to filter blood and concentrate filtered wastes into urine. Here, we present the rationale for design and technology choices and describe progress toward the goal of an implantable BioArtificial Kidney.

Indexed as

KidneyKidneys, ArtificialKidney TransplantationLiving DonorsTissue DonorsHumansESKDkidney transplantationorgan transplantrenal epithelial cellrenal proximal tubule cellrenal transplantationtransplantationtubular epithelium

Identifiers

PMID41165755
PMCPMC13134794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.