Evidence map›Paper›PMID 41165640›Full record

ArticleJACC. Case reports2025

Acute Left Ventricular Dysfunction After Mitral Transcatheter Edge-to-Edge Repair.

Luca Raone, Marco Ferlini, Francesco Maria Sparasci, Costantino Pelosi, Daniele Cucchi, Silvia Miette Pontremoli, Giuseppe Lanzillo, Giulia Magrini, Rita Camporotondo, Leonardo De Luca

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luca RaoneDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address: raone.luca@gmail.com.
Marco FerliniDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Francesco Maria SparasciDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Costantino PelosiDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Daniele CucchiDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Silvia Miette PontremoliDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Giuseppe LanzilloDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Giulia MagriniDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Rita CamporotondoDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Leonardo De LucaDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitral transcatheter edge-to-edge repair (M-TEER) is an established treatment for severe mitral regurgitation. However, acute left ventricular (LV) dysfunction may complicate the procedure through mechanisms with distinct implications. CASE SUMMARY: An 81-year-old man with severe primary mitral regurgitation underwent elective M-TEER. Immediately after clip deployment, he developed acute LV dysfunction, initially managed as afterload mismatch (AM) with vasodilators. The clinical evolution was associated with apical ballooning on echocardiography, with electrocardiographic changes and troponin elevation without obstructive coronary disease, supporting Takotsubo syndrome (TTS). The patient remained stable, and LV function fully recovered within 1 week. DISCUSSION: This case illustrates the difficulty of distinguishing AM from TTS after M-TEER, 2 entities with overlapping features but different prognostic and therapeutic implications. TAKE-HOME MESSAGES: Acute LV dysfunction after M-TEER should not be automatically attributed to AM. TTS should be considered, and the integration of clinical, echocardiographic, and electrocardiographic findings is essential to management.

Indexed as

acute heart failureechocardiographyhemodynamicsmitral valve

Identifiers

PMID41165640
PMCPMC12861658

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.