Evidence map›Paper›PMID 41165606›Full record

ArticleJournal of applied clinical medical physics2025

A multi-institution performance assessment of a double-layer MLC.

Andy Buckle, Conor Heeney, Matthew Jones, Vasu Ganesan, Ronan Valentine, Philip Wheeler, James Earley, Garry Grogan, Matthew Sparks

Abstract readMulticenter Study
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A multi-institution performance assessment of a double-layer MLC.Journal of applied clinical medical physics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andy BuckleOxford University Hospitals NHS Foundation Trust, Radiotherapy Physics, Churchill Hospital, Oxford, UK.
Conor HeeneyMid-Western Radiation Oncology Centre, Mater Private Network, Mid-Western Radiation Oncology Centre, University Hospital Limerick, Dooradoyle, Limerick, Ireland.
Matthew JonesRoyal Surrey County Hospital NHS Foundation Trust, Royal Surrey County Hospital, Guildford, UK.
Vasu GanesanBarking, Havering and Redbridge University Hospital NHS Trust, Queen's Hospital, Romford, UK.
Ronan ValentineThe Beatson West of Scotland Cancer Centre, Gartnavel General Hospital, Glasgow, UK.
Philip WheelerVelindre University NHS Trust, Velindre Cancer Centre, Cardiff, UK.
James EarleyRoyal Surrey County Hospital NHS Foundation Trust, Royal Surrey Cancer Centre, Guildford, UK.
Garry GroganOxford University Hospitals NHS Foundation Trust, Radiotherapy Physics, Churchill Hospital, Oxford, UK.
Matthew SparksUniversity Hospitals Sussex NHS Foundation Trust, Sussex Cancer Centre, Brighton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarian Halcyon and Ethos linacs use a novel double-layer MLC. PURPOSE: To perform a multi-institutional characterization of MLC performance of Varian Halcyon and Ethos linacs and establish the range of typical performance indices.

methodsThe tests used plans delivered to the megavoltage (MV) imaging panel that can be easily implemented and reproducibly delivered in different centers. Automated image analysis was used to obtain metrics that characterize the MLC performance. The tests included picket fence, MLC leakage, sweeping gap, open field symmetry changes, change of output with gantry angle, and volumetric modulated arc therapy (VMAT) indices. Sixteen linacs from 11 centers were included in the study.

resultsPerformance indices were found that are in line with other linacs, with the exception of proximal layer positional calibration.

conclusionsTypical ranges have been established for Halcyon/Ethos MLC performance indices.

Indexed as

NeoplasmsParticle AcceleratorsPhantoms, ImagingRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedCalibrationHumansQuality Assurance, Health CareRadiotherapy DosageauditHalcyonMLCQA

Identifiers

PMID41165606
PMCPMC12574430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.