Evidence map›Paper›PMID 41165327›Full record

ArticleJournal of virology2025

Viral RNA pUGylation promotes antiviral immunity in

David D Lowe, Aditi Shukla, Scott G Kennedy

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The microRNAmicroPublication biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

David D LoweDepartment of Genetics, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-2322-3437
Aditi ShuklaWhitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.ORCID 0000-0001-9743-4128
Scott G KennedyDepartment of Genetics, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-7974-8155

Funding

Non-Coding RNAs in Gene Regulation, Genome Defense, and Epigenetic InheritanceR35GM148206 · NIGMS · HARVARD MEDICAL SCHOOL · PI Scott G Kennedy · 2023 to 2026
$2.7M
Genetics and Genomics PhD Training GrantT32GM096911 · NIGMS · HARVARD MEDICAL SCHOOL · PI KENNEDY, SCOTT G · 2011 to 2020
$2.5M
National Science Foundation DGE1144152National Science Foundation DGE1745303National Science Foundation DGE2140743NIGMS NIH HHS R35 GM148206NIGMS NIH HHS T32 GM096911NIH HHS NIH 5T32GM096911-10NIH HHS R35GM148206
6 · The paper itself

Abstract

RNA interference (RNAi) is a component of the innate immune systems of many eukaryotes, including

Indexed as

Caenorhabditis elegansRNA, ViralAnimalsCaenorhabditis elegans ProteinsImmunity, InnateNodaviridaeNucleotidyltransferasesRNA-Dependent RNA PolymeraseRNA InterferenceRNA, Small InterferingVirus ReplicationCaenorhabditis elegans ProteinsNucleotidyltransferasesRNA-Dependent RNA PolymeraseRNA, Small InterferingRNA, Viralantiviral RNAiC. elegansOrsay viruspoly(UG) RNApUGasomesmall RNA

Identifiers

PMID41165327
PMCPMC12645942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.