Evidence map›Paper›PMID 41165302›Full record

ArticleEnvironmental science & technology2025

Identifying Novel DNA Adducts in Amphipods and Developing Sample Preparation for Adductomics Using Dispersive Solid-Phase Extraction.

Zareen Khan, Elena Gorokhova, Giulia Martella, Nisha H Motwani, Natalia Tretyakova, Pedro F M Sousa, Hitesh V Motwani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zareen KhanDepartment of Environmental Science, Stockholm University, Stockholm SE-106 91, Sweden.ORCID 0000-0001-6975-3906
Elena GorokhovaDepartment of Environmental Science, Stockholm University, Stockholm SE-106 91, Sweden.ORCID 0000-0002-4192-6956
Giulia MartellaDepartment of Environmental Science, Stockholm University, Stockholm SE-106 91, Sweden.
Nisha H MotwaniSchool of Natural Sciences, Technology and Environmental Studies, Södertörn University, Huddinge SE-14189, Sweden.ORCID 0000-0002-5291-5929
Natalia TretyakovaDepartment of Medicinal Chemistry and Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-0621-6860
Pedro F M SousaDepartment of Materials and Environmental Chemistry, Stockholm University, Stockholm SE-106 91, Sweden.ORCID 0000-0002-5131-6326
Hitesh V MotwaniDepartment of Environmental Science, Stockholm University, Stockholm SE-106 91, Sweden.ORCID 0000-0002-0998-0266

Funding

Untargeted Adductomics to Characterize Ethnic Differences in the Exposome of SmokersP01CA138338 · NCI · UNIVERSITY OF MINNESOTA · PI Daniel O Stram · 2010 to 2026
$33.4M
Smoking-Induced Epigenetic Changes in the Lung: Role of DNA DemethylationR01CA095039 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI TRETYAKOVA, NATALIA Y · 2003 to 2022
$3.6M
Sequence Distribution of Tabacco Carcinogen-DNA AdductsR56CA095039 · NCI · UNIVERSITY OF MINNESOTA · PI TRETYAKOVA, NATALIA Y · 2007 to 2007
$237k
NCI NIH HHS P01 CA138338NCI NIH HHS R01 CA095039NCI NIH HHS R56 CA095039
6 · The paper itself

Abstract

The growing use of environmental DNA adductomics for exposure assessment emphasizes the need for improved methods that are adapted to chemically and biologically diverse samples. While liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) has advanced DNA adductome analysis, sample cleanup methods remain challenging, especially in nonmammalian models. Here, we used amphipod

Indexed as

AmphipodaDNA AdductsAnimalsSolid Phase ExtractionDNA Adductsdispersive solid-phase extractionDNA adductsexposure assessmenthigh-resolution mass spectrometrynontarget analysis

Identifiers

PMID41165302
PMCPMC12631988

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.