Evidence map›Paper›PMID 41165069›Full record

ArticleThe Laryngoscope2026

Dysphagia Characteristics in High Versus Low Vagal Unilateral Vocal Fold Paralysis.

Madeline Miles Marker, Liam W Gallagher, Aanish Puri, Jesse Hoffmeister, Scott Lunos, Heather Erickson, Gina Cruciani, Joslyn Kahn, Stephanie Misono, Raluca Gray

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Madeline Miles MarkerDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0009-0005-5350-4709
Liam W GallagherDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.
Aanish PuriDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0009-0007-8726-9000
Jesse HoffmeisterDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.
Scott LunosBiostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota, USA.
Heather EricksonM Health Fairview Rehab Services, Minneapolis, Minnesota, USA.
Gina CrucianiM Health Fairview Rehab Services, Minneapolis, Minnesota, USA.
Joslyn KahnM Health Fairview Rehab Services, Minneapolis, Minnesota, USA.
Stephanie MisonoDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-9000-6323
Raluca GrayDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0003-3403-2345

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · NCATS · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar, Damien A Fair · 2023 to 2026
$30.8M
CTSA K12 Program at University of MinnesotaK12TR004373 · NCATS · UNIVERSITY OF MINNESOTA · PI David H Ingbar · 2024 to 2026
$3.2M
NCATS NIH HHS K12 TR004373NCATS NIH HHS UM1 TR004405
6 · The paper itself

Abstract

objectiveTo compare instrumental swallow assessment findings and diet recommendations in high versus low vagal unilateral vocal fold paralysis (UVFP).

methodsRetrospective review of patients with UVFP who underwent instrumental swallow assessment, September 2019-February 2024. Demographics, Eating Assessment Tool-10 (EAT-10) score, flexible laryngoscopy findings, instrumental swallow parameters, diet recommendations, treatment modalities, and posttreatment outcomes were analyzed.

resultsNinety-six patients were included: 28 (29%) high-vagal and 68 (71%) low-vagal UVFP. High vagal UVFP had a higher incidence of premature spillage (57% vs. 13%, p < 0.0001); residue (82% vs. 22%, p < 0.0001), penetration (89% vs. 35%, p < 0.0001), aspiration (50% vs. 22%, p = 0.013), modified diet (61% vs. 16%, p < 0.0001), and behavioral modifications (89% vs. 38%, p < 0.001) compared to low vagal UVFP. Thirty-one patients (32%) underwent injection laryngoplasty (16 high, 15 low vagal) with similar pretreatment prevalences of premature spillage, penetration, and aspiration, but a higher prevalence of residue in the high vagal group (100% vs. 53%, p = 0.002). Both groups improved posttreatment (high vagal: 63%-19%, p = 0.016; low vagal: 80%-7%, p = 0.001).

conclusionHigh vagal UVFP is associated with greater swallowing dysfunction and higher prevalences of diet and behavioral modifications compared to low vagal UVFP. Treated high and low vagal subgroups had similar dysphagia profiles. Injection laryngoplasty improved aspiration, regardless of vagal level, although many patients continued to require behavioral modifications. Future studies are needed to identify predictors of poor functional swallowing outcomes in UVFP. LEVEL OF EVIDENCE: 3:

Indexed as

Deglutition DisordersVocal Cord ParalysisAdultAgedFemaleHumansLaryngoplastyLaryngoscopyMaleMiddle AgedRetrospective Studiesdysphagialevel of vagal injuryunilateral vocal fold paralysis

Identifiers

PMID41165069
PMCPMC12629264

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.