Evidence map›Paper›PMID 41165062›Full record

ArticleBiometrical journal. Biometrische Zeitschrift2025

Sparse Canonical Correlation Analysis for Multiple Measurements With Latent Trajectories.

Nuria Senar, Aeilko H Zwinderman, Michel H Hof

Abstract read
In one paragraph

Article in Biometrical journal. Biometrische Zeitschrift, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nuria SenarDepartment of Epidemiology & Data Science, Amsterdam School of Public Health, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0002-1004-5785
Aeilko H ZwindermanDepartment of Epidemiology & Data Science, Amsterdam School of Public Health, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0003-0361-3139
Michel H HofDepartment of Epidemiology & Data Science, Amsterdam School of Public Health, Amsterdam UMC, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canonical correlation analysis (CCA) is a widely used multivariate method in omics research for integrating high-dimensional datasets. CCA identifies hidden links by deriving linear projections of observed features that maximally correlate datasets. An important requirement of standard CCA is that observations are independent of each other. As a result, it cannot properly deal with repeated measurements. Current CCA extensions dealing with these challenges either perform CCA on summarized data or estimate correlations for each measurement. While these techniques factor in the correlation between measurements, they are suboptimal for high-dimensional analysis and exploiting this data's longitudinal qualities. We propose a novel extension of sparse CCA that incorporates time dynamics at the latent variable level through longitudinal models. This approach addresses the correlation of repeated measurements while drawing latent paths, focusing on dynamics in the correlation structures. To aid interpretability and computational efficiency, we implement an

Indexed as

BiometryCorrelation of DataHumansModels, Statisticalcanonical correlation analysisdimension reductionhigh‐dimensional datarepeated measurements

Identifiers

PMID41165062
PMCPMC12573309

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.