SynthesisDevelopmental medicine and child neurology2026
Gastroenterological disorders and hepatic disease in adults with cerebral palsy: A systematic review.
Synthesis in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gastroenterological disorders and hepatic disease in adults with cerebral palsy: A systematic review.Developmental medicine and child neurology · 2026Pooled it
- Elevated Rates of Gastrointestinal Dysfunction in Children with Neurodevelopmental Disabilities: Not Just an Autism Issue.medRxiv : the preprint server for health sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
aimTo describe the incidence, prevalence, and prognostic factors for gastroenterological disorders and hepatic disease in adults with cerebral palsy (CP), and to examine the effectiveness of any screening or interventions.
methodSix databases were searched for articles published in any language since 1990 meeting eligibility criteria, defined for each of five objectives. Two independent reviewers screened study titles, abstracts, and full texts for inclusion.
resultsThirty-two reports of 30 unique samples, including 10 to 16 818 adults, were identified. Twenty-five reported prevalence of at least one of the following: gastroesophageal reflux disease (GERD) (prevalence 3%-42%; seven studies), constipation (4%-67%; seven studies), dysphagia (6%-77%; 12 studies), fecal incontinence (6%-29%; three studies), dental/oral cavity disorders (25%-53%; five studies), and aggregated hepatic diseases (1%-6%; seven studies). The prevalences of GERD, dysphagia, and hepatic disease were higher in adults with CP than in those without. The prevalence of fecal incontinence was greater in people classified as having CP in higher Gross Motor Function Classification System levels. No incidence studies were identified. Four intervention studies addressing oral/dental health or dysphagia were found, but certainty of evidence was low to very low.
interpretationThe prevalence of specific gastroenterological disorders and hepatic disease varies across studies in adults with CP. Evidence for intervention efficacy in their management is of very low quality to absent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.