ArticleFrontiers in public health2025
Global, regional, and national differences in the incidence and mortality of digestive congenital anomalies from 1990 to 2021, with projections for future trends.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Global prognostic factors for mortality and major postoperative morbidity in neonatal intestinal atresia in the modern surgical era: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Digestive congenital anomalies (DCA) remain a major yet unevenly distributed cause of death and disability worldwide. We aimed to quantify global, regional, and national trends in DCA prevalence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021. Methods: We analyzed Global Burden of Disease 2021 data. Age-standardized rates and estimated annual percentage changes were calculated for five age groups: <1 year, 2-4 years, 5-14 years, 15-19 years, and 20-54 years. Future trajectories to 2036 were projected using an autoregressive integrated moving average (ARIMA) model. Results: In 2021, infants accounted for the largest share of the burden, although their absolute incidence declined by 9% relative to 1990. High-socio-demographic index (SDI) regions achieved pronounced reductions in both mortality and DALYs, whereas low-SDI regions showed rising trends. Projections indicate a continued global increase in prevalence across all age groups, alongside further declines in infant and child mortality. Discussion: Persistent inequities underscore the need for strengthened maternal-neonatal services, early surgical access, and targeted resource allocation in low-income settings. This integrated epidemiological overview provides an evidence base for prioritizing DCA within national child-health agendas and for monitoring progress toward Sustainable Development Goal targets.
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