Evidence map›Paper›PMID 41164813›Full record

ArticlePrecision radiation oncology2025

Dosimetric assessment of conventional and advanced algorithms in clinical stereotactic radiotherapy.

Abhay Kumar Singh, Anuj Vijay, Manindra Bhushan

Abstract read
In one paragraph

Article in Precision radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Tightening the gradient: ten years of dosimetric refinement in head and neck reirradiation.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  2. Article
  3. Targeting gut microbiota and metabolites in cancer radiotherapy.Clinical and translational medicine · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abhay Kumar SinghDepartment of Physics, GLA University Mathura India.ORCID https://orcid.org/0009-0004-7917-7841
Anuj VijayDepartment of Physics, GLA University Mathura India.
Manindra BhushanDepartment of Radiation Oncology, Division of Medical Physics Rajiv Gandhi Cancer Institute and Research Centre New Delhi India.ORCID https://orcid.org/0000-0002-2050-4375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To systematically compare the dosimetric performance of conventional (Ray Tracing, AAA) and advanced (Monte Carlo, Acuros XB) dose calculation algorithms across homogeneous and heterogeneous tissues in stereotactic radiotherapy (SRT) and stereotactic body radiotherapy (SBRT). Methods: A retrospective analysis of 125 SRT cases (brain: 50, lung: 20, liver: 20, spine: 35) was conducted using CyberKnife and Varian systems. Plans were originally created using Type B (Anisotropic Analytical Algorithm [AAA] and Ray Tracing) algorithms and were subsequently recalculated using Type C (Acuros XB and Monte Carlo) algorithms, while maintaining identical beam geometry and monitor units. Dosimetric parameters (D Results: In lung cases, Type B algorithms overestimated D Conclusion: Advanced algorithms demonstrated superior dose accuracy, homogeneity, and organs at risk (OAR) sparing in heterogeneous anatomical regions. Despite higher computational requirements, their clinical implementation is justified for SRT/SBRT planning. This study supports a site-specific approach, advocating for advanced algorithm use in anatomically complex scenarios.

Indexed as

acuros XBdose calculation algorithmsheterogeneous tissuesMonte Carlostereotactic radiotherapy

Identifiers

PMID41164813
PMCPMC12559905

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.