Evidence map›Paper›PMID 41164751›Full record

ArticleFrontiers in pharmacology2025

Identification of an anti-inflammatory action of exosome release in P2Y

Esteban Diaz Villamil, Paul Rouvier, Michael Horckmans, Lucas De Roeck, Erika Hendrickx, Louise Conrard, Didier Communi

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esteban Diaz Villamil *Institute of Interdisciplinary Research, IRIBHM, Free University of Brussels, Brussels, Belgium.
Paul Rouvier *Institute of Interdisciplinary Research, IRIBHM, Free University of Brussels, Brussels, Belgium.
Michael HorckmansInstitute of Interdisciplinary Research, IRIBHM, Free University of Brussels, Brussels, Belgium.
Lucas De RoeckInstitute of Interdisciplinary Research, IRIBHM, Free University of Brussels, Brussels, Belgium.
Erika HendrickxCenter for Microscopy and Molecular Imaging (CMMI), Université Libre de Bruxelles, Gosselies, Belgium.
Louise ConrardCenter for Microscopy and Molecular Imaging (CMMI), Université Libre de Bruxelles, Gosselies, Belgium.
Didier CommuniInstitute of Interdisciplinary Research, IRIBHM, Free University of Brussels, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Exosomes are major actors in the progression of cardiovascular diseases and potential associated-treatments. We showed previously that inactivation of the mouse P2Y Methods and results: Interestingly the reduction of cardiac fibrosis and T cell infiltration observed in P2Y Discussion: These data support the role of the release of anti-inflammatory exosomes, and more particularly the exosomal form of PD-L1 and adiponectin, in P2Y

Indexed as

cardioprotectionexosomeischemiaP2Y receptorPD-L1

Identifiers

PMID41164751
PMCPMC12558736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.