Evidence map›Paper›PMID 41164629›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Post-COVID-19 Complications: A Study on Long COVID Symptoms and Their Pathophysiology.

Priyanka Sekar, Melvin Dominic, Sudhiersharan Balakrishnan, V K Sreelakshmi, R Haneendhar, S Jithin Gopan, Pragnesh Rathnasami, Sai Vineeth Moturi

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Priyanka SekarDepartment of General Medicine, Pondicherry Institute of Medical Sciences, Pondicherry University, Pondicherry, Tamil Nadu, India.
Melvin DominicDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.
Sudhiersharan BalakrishnanDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.
V K SreelakshmiDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.
R HaneendharDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.
S Jithin GopanDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.
Pragnesh RathnasamiDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.
Sai Vineeth MoturiDepartment of Emergency Medicine, Vinayaka Missions Kirupananda Variyar Medical College and Hospital, Vinayaka Mission Research Foundation, Salem, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long COVID refers to persistent symptoms lasting weeks or months after recovery from acute COVID-19. These symptoms can affect multiple systems and impair quality of life. Objective: To assess the prevalence, pattern, and probable pathophysiological mechanisms of long COVID symptoms in recovered patients. Materials and Methods: A cross-sectional study was conducted over 12 months among 210 adults recovered from COVID-19 (≥12 weeks postinfection). Clinical evaluation, lab investigations, and imaging were used to identify post-COVID symptoms and explore underlying mechanisms. Results: Common symptoms included fatigue (67.6%), breathlessness (42.8%), cognitive issues (39.5%), and myalgia (34.7%). Neuropsychiatric complaints were noted in 41%, while 29% had cardiopulmonary sequelae. Elevated inflammatory markers correlated with symptom persistence ( Conclusion: Long COVID involves diverse symptoms, primarily fatigue and neurorespiratory complaints. Immune dysregulation and systemic inflammation appear central to its pathophysiology.

Indexed as

Breathlessnessfatigueinflammationlong COVIDpost-viral syndrome

Identifiers

PMID41164629
PMCPMC12563606

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.