ArticleJournal of pharmacy & bioallied sciences2025
A Cross-Sectional Study on the Sociodemographic Profile of Sickle Cell Disease and Quality of Life in the Pediatric Age Group Among the Tribal Population Of Madhya Pradesh.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Sickle cell disease (SCD) is among the most prevalent hereditary hemoglobinopathies worldwide. Objectives: A cross-sectional study was conducted on the sociodemographic profile of sickle cell disease and quality of life in the pediatric age group among the tribal population of Madhya Pradesh. Materials and Methods: We conducted a cross-sectional, hospital-based enrolling 100 homozygous SCD [SS pattern] pediatric participants aged 8-18 years, and 100 healthy controls. We assessed sociodemographic variables and clinical data. health-related quality of life (HRQoL) was measured using the WHOQOL-BREF questionnaire in local language and Domain scores were compared between groups. Results: Children with SS pattern demonstrated significantly lower HRQoL scores than controls in all domains ( Conclusion: In this tribal cohort, homozygous SCD imposes substantial burdens on HRQoL, compounded by sociodemographic disadvantages.
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