Evidence map›Paper›PMID 41164586›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Photodynamic Therapy versus Surgery in Management of Oral Squamous Cell Carcinoma: A Comparative Study.

Debajyoti Bardhan, Digvijaysinh Parmar, Amartya Prakash Srivastava, Sailaja Sanda, Jagadish Prasad Panda, Urvashi A Shetty, Praveen Kumar Varma Datla, Lubna Tabassum Siddiqui

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Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Debajyoti BardhanDepartment of Oral Medicine and Radiology, Hi-Tech Dental College and Hospital, Bhubaneswar, Odisha, India.
Digvijaysinh ParmarDental Public Health (DPH) Residency Program, University of California, San Francisco, California, USA.
Amartya Prakash SrivastavaDepartment of Oral and Maxillofacial Surgery, Chandra Dental College and Hospital, Lucknow, Uttar Pradesh, India.
Sailaja SandaBDS, Government Dental College, Kadapa, Andra Pradesh, India.
Jagadish Prasad PandaIntern, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneswar, Odisha, India.
Urvashi A ShettyDepartment of Oral and Maxillofacial Pathology and Oral Microbiology, AB Shetty Memorial Institute of Dental Sciences, Nitte- Deemed to be University, Mangalore, Karnataka, India.
Praveen Kumar Varma DatlaDepartment of Orthodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
Lubna Tabassum SiddiquiDepartment of Periodontics, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: "Oral squamous cell carcinoma (OSCC)" is one of the most common malignancies of the oral cavity, often requiring aggressive surgical intervention. "Photodynamic therapy (PDT)" has emerged as a minimally invasive treatment option to enhance the efficacy of surgical treatments. The combination of PDT with surgery has been suggested to reduce recurrence rates and improve overall outcomes. Methods: This research aims to evaluate the efficacy of PDT as an adjunct to surgery in treating OSCC, using three key parameters: tumor recurrence rates, survival outcomes, and postoperative complications. A cohort of OSCC patients treated with surgery alone was compared with a cohort treated with both surgery and PDT. Results: Patients treated with surgery and PDT demonstrated significantly lower tumor recurrence rates ( Conclusion: PDT as an adjunct to surgery shows promise in improving recurrence rates and survival outcomes in OSCC without increasing postoperative complications. Further large-scale studies are needed to confirm these findings.

Indexed as

Oral squamous cell carcinomaphotodynamic therapyrecurrencesurgerysurvival

Identifiers

PMID41164586
PMCPMC12564073

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