Evidence map›Paper›PMID 41164545›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Evaluation of Effectiveness of Silver Diamine Fluoride in Arresting Early Childhood Caries: A Prospective Study.

Anjumoni Daimary, Rajnish K Verma, Linda F Mirza, Rabab Musalli, Renie K Dewi, Srikala Bhandary, Mohammed M Khan, Raj K Dangi

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anjumoni DaimaryDepartment of Pediatric Dentistry, Rupnagar, Guwahati, Assam, India.
Rajnish K VermaDepartment of Pediatric and Preventive Dentistry, Kalinga Institute of Dental Sciences, Campus 5, KIIT University, Patia, Bhubaneswar, Odisha, India.
Linda F MirzaPediatric Dentist Consultant, King Abdullah Medical Complex, Ministry of Health, Jeddah, Saudi Arabia.
Rabab MusalliKing Abdulaziz Medical City, Jeddah, Saudi Arabia.
Renie K DewiDepartment of Pediatric Dentistry, Faculty of Dentistry, Lambung Mangkurat University, Banjarmasin, Kalimantan Selatan, Indonesia.
Srikala BhandaryDepartment of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangaluru, Karnataka, India.
Mohammed M KhanMinistry of Health, Taif, Kingdom of Saudi Arabia.
Raj K DangiDepartment of Oral and Maxillofacial Surgery, RKDF Dental College and Research Centre, Bhopal, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Silver diamine fluoride (SDF) is a minimally invasive option for the arrest of early childhood caries (ECC). Its usage has been associated with significant reductions in caries progression, providing a cost-effective solution in pediatric dental care. This research aims to evaluate the efficacy of SDF compared to sodium fluoride varnish in arresting ECC in preschool children. Methods: This randomized controlled trial included 120 preschool children aged 2-5 years with diagnosed ECC. Participants were randomly assigned to receive either 38% SDF application or sodium fluoride varnish. The primary outcome was caries arrest rate, measured at 6 months. Secondary outcomes included parental satisfaction and child "oral health-related quality of life (OHRQoL)". Data analysis was performed using Chi-square and t-tests for comparison between groups. Results: At the 6-month follow-up, children who received SDF treatment demonstrated a significantly higher caries arrest rate (85%) compared to those who received sodium fluoride varnish (50%) ( Conclusion: SDF is a highly effectual treatment for arresting ECC in preschool children, offering a more efficacious option compared to traditional fluoride varnish treatments. Its application is well accepted by parents and positively impacts children's OHRQoL.

Indexed as

Early childhood cariesfluoride varnishpediatric dentistryrandomized controlled trialsilver diamine fluoride

Identifiers

PMID41164545
PMCPMC12563730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.