Evidence map›Paper›PMID 41164543›Full record

ArticleJournal of pharmacy & bioallied sciences2025

To Compare Opioid Based versus Opioid-Free Anesthesia (Integrating with Erector Spinae Plane Block) in Laparoscopic Surgeries - A Prospective Study.

Monika Gandhi, Nelapati Mouna, Aseem Sharma, Prachi Shukla, Manish Banjare

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Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monika GandhiDepartment of Anesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India.
Nelapati MounaDepartment of Anesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India.
Aseem SharmaDepartment of Anesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India.
Prachi ShuklaDepartment of Radiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India.
Manish BanjareDepartment of Anesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Opioid-free anesthesia (OFA) using multimodal analgesia and erector spinae plane block (ESPB) has shown promise in reducing opioid-related side effects in laparoscopic surgeries. We compared postoperative pain scores, intraoperative hemodynamics, analgesic requirements, and side effects between OFA with ESPB and opioid-based anesthesia (OBA). Material and Methods: Sixty patients undergoing elective laparoscopic surgery were randomized into two groups ( Results: VAS scores were significantly lower in Group A at 1, 2, 3, 4, 16, and 24 h postoperatively ( Conclusion: OFA with ESPB provides superior postoperative analgesia, better hemodynamic stability, and reduces opioid consumption and related side effects in laparoscopic surgeries.

Indexed as

Erector spinae plane blockhemodynamic stabilitylaparoscopic surgerymultimodal analgesiaopioid-free anesthesiapostoperative pain

Identifiers

PMID41164543
PMCPMC12563629

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.