ArticleJournal of pharmacy & bioallied sciences2025
The Effectiveness of Different Intracanal Medicaments in Treating Apical Periodontitis.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Apical periodontitis is frequently the result of a pulpal infection, mainly brought on by bacterial entry and the body's response to infection. A root canal system needs to be properly disinfected to achieve the success of endodontic therapy. Materials and Methods: Single-rooted human teeth replicating apical periodontitis were below the root end, and their surfaces were mechanically prepared by rotary NiTi instruments to size F3. We separated the samples into four teams of 12, with the control being saline. Group I received calcium hydroxide, Group II had triple antibiotic paste, Group III got 2% chlorhexidine (CHX) gel, and Group IV received saline. Once the tissue common to human and root canal system was infected with Results: Every experimental group was shown to have fewer CFUs, on average, than the control group ( Conclusion: Triple antibiotic paste was the top choice among all tested medicaments with strong antimicrobial activity against
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