Evidence map›Paper›PMID 41164325›Full record

ArticleJournal of experimental orthopaedics2025

Near-normal ultrasound morphology in quadriceps tendon after anterior cruciate ligament graft harvest.

Jumpei Inoue, Kohei Kamada, Keishi Takaba, M Enes Kayaalp, Joseph D Giusto, Bryson P Lesniak, Andrew L Sprague, Volker Musahl

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jumpei InoueUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0003-3953-5646
Kohei KamadaUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
Keishi TakabaUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
M Enes KayaalpUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
Joseph D GiustoUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
Bryson P LesniakUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
Andrew L SpragueDepartment of Physical Therapy, School of Health and Rehabilitation Sciences University of Pittsburgh Pittsburgh Pennsylvania USA.
Volker MusahlUPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.

Funding

Graft harvest as a model of tendon injury; Trajectory of recovery and clinical outcomesK23AR080741 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Andrew L Sprague · 2022 to 2026
$608k
NIAMS NIH HHS K23 AR080741
6 · The paper itself

Abstract

Purpose: The quadriceps tendon (QT) autograft is increasingly used for anterior cruciate ligament reconstruction (ACLR) due to favourable clinical outcomes. However, the long-term morphological and vascular changes at the QT harvest site remain unclear. This study aimed to evaluate QT morphology and vascularity using ultrasound at least 1 year after ACLR. Methods: Thirty-five patients who underwent ACLR with a QT autograft were prospectively evaluated at a mean of 3.4 ± 3.5 years post-operatively. Surgical technique was not standardized with respect to harvest thickness or bone block inclusion. Ultrasound was used to assess anterior-to-posterior (A-P) thickness, medial-to-lateral (M-L) width, cross-sectional area (CSA) and echogenicity of the QT in both knees at 15, 30, 45 and 60 mm proximal to the patella. Superb microvascular imaging (SMI) was employed to evaluate vascularity at the same locations. Comparisons were made between the operated and contralateral sides. Results: A-P thickness was significantly greater in the operated knee at 30 mm (by 0.7 mm, Conclusion: QT morphology generally normalized by 3.4 years post-ACLR, although reduced echogenicity persisted, suggesting potential changes in tendon quality. Despite these findings, no clinical complications were observed, supporting the long-term safety of QT autograft harvest for ACLR. Level of Evidence: Level IV.

Indexed as

anterior cruciate ligament reconstructiongraft survivalquadriceps muscletendons/diagnostic imagingultrasonography

Identifiers

PMID41164325
PMCPMC12560256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.